更新时间：2024-09-21 18:53
吕海涛博士，上海交通大学系统生物医学研究院 研究员/课题组长/博导
2004.09-2009.06 黑龙江中医药大学 药学院 生药学（硕博连读）博士学位
2000.09-2004.07 黑龙江中医药大学 药学院 中药学 学士
2016.09-至今 上海交通大学系统生物医学研究院 研究员/课题组长/博导
2013.07-至今 QUT Vice Chancellor’s Fellowship (国际人才基金，Adjunct Faculty）
2012.09-2016.09 重庆大学药学院（创新药物研究中心）百人计划研究员/博导/主任助理
2009.09-2013.01 美国爱因斯坦医学院/华盛顿大学医学院/麻省理工学院 博士后研究员
QUT校长特聘教授席人才基金
重庆大学百人计划
上海交通大学特聘研究员
学会兼职与审稿人
中华中西医结合学会中医方证代谢组学分会副会长（筹）
世中联网络药理学专委会常务理事
中国药理学会网络药理学专委会理事
中国药理学学会分析药理学专委会创会理事
国际代谢组学学会会员
Phytomedicine (IF 3.6)副主编
Frontiers in Microbiology（IF 4.0）副主编
Frontiers in Pharmacology (IF 3.8) 副主编
Scientific Reports (IF 4.1) 编委
Bioanalysis (IF 2.65) 编委
Acta Pharmaceutica Sinica B (IF 6.0) 青年编委
Chinese Journal of Natural Medicines (IF 1.9) 青年编委
1. 国家重点研发计划; 胰腺癌转移的阶段化代谢特征谱及代谢机理研究/ 2017YFC1308605；2017.06－2020.12; 获批经费：334.0万；主持人；在研
2. 国家自然科学基金面上项目；致病性大肠杆菌中新铁载体的发现与功能表征/C010201； 2017.01-2020.12；获批经费：62.0万；主持人；在研
3. 国家自然科学基金面上项目；基于代谢组学技术表征中药石韦治疗尿路感染的活性组分和作用机制/81274175；2013.01-2016.12；获批经费：70.0万；主持人；结题
4. 重庆自然基金面上项目；基于代谢组学技术表征中药人参治疗糖尿病的功能组分和作用机理/CSTC2014JCYIA10109；2014.09-2017.09；获批经费：5.0万；主持人；结题
5. 中央高校基本科研业务费学校创新重大项目；新铁载体的发现与表征/ 2015CDJZR；2015.07-2017.07；获批经费：50.0万；主持人；结题
6. 中央高校基本科研业务费跨学科重大项目；基于代谢组学技术的人参治疗糖尿病的转化医学研究
/ CQDXWL-2014-Z002；2014.06-2017.06；获批经费：35.0万；主持人；在研
7. QUT Vice Chancellor's Research Fellowships（国际人才基金）；群体性肌肉损伤代谢生物标记物的发现与表征/ 150410-0070/08；2013.07-2016.07；获批经费：150.0万；主持人；结题
1.
Luo, X., Guo, R., Xu, X., Li, X., Yao, L., Wang, X., and Lu, H*. (2018) Spectrometry And Associated Technologies Delineate The Advantageously Biomedical Capacity Of SiderophoresIn Different Pathogenic Contexts. 质量 Spectrometry Reviews, doi: 10.1002/mas.21577(Invited by Editor in Chief)(*Correspond荷兰 Author)
2.
Su, Q, Xu, G. Guan, T. Que, Y. and Lu, H*. (2018). Mass spectrometry-derived systems biology technologies delineate the system's applications of siderophores with 化学 and biology. 质量 Spectrometry Reviews, 37, 188-201(Invited by Editor in Chief) (*Corresponding Author)
3.
Su, Q., Guan, T. B., He, Y. and Lv, H*. (2016). Siderophore biosynthesis governs the virulence of uropathogenic 埃希氏菌属 coli by coordinately modulating the differential 新陈代谢 Journal of Proteome Research, 15, 1323-1332. (*Corresponding Author)
4.
Nie, W.N., Yan, L. Y. Lee, Y. H., Guha, C., Kurland, I. J., and Lu, H.T.,* (2016). Advanced 质量 spectrometry based multiple omics technologies for exploring the pathogenesis of hepatocellular carcinoma. Mass Spectrometry Reviews, 35, 331-349. (*Corresponding Author)
5.
Nie, W., Lv, Y., Yan, L., Chen, X. and Lv, H*. (2015): Prediction and Characterization of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms. Scientific Reports 5, 17646; doi: 10.1038/srep17646. (*Corresponding Author)
6.
Lv, H. T*., Hung, C. S., and Henderson, J. P.* (2014): Metabolomic Analysis of Siderophore Cheater Mutants Reveals Metabolic Costs of Expression in Uropathogenic 埃希氏菌属 coli. Journal of Proteome Research, 13, 1397-1404. (*Corresponding Author)
7.
Lv, H. T.* (2013): 质量 spectrometry based metabolomics towards understanding of gene functions with a diversity of biological contexts, Mass Spectrometry Reviews, 32, 118-128. (*Corresponding Author)
8.
Lv, H.T., and Henderson, J. P. (2011): 耶尔森菌属 High Pathogenicity Island genes modify the Escherichia coli primary metabolome independently of siderophore production. Journal Proteome Research, 10, 5547-5554.
9.
Lv, H.T., Palacios, G., Hartil, K. and Kurland, I.J. (2011): Advantages of Tandem LC-MS for the Rapid Assessment of Tissue-specific Metabolic Complexity using a Pentafluorophenylpropyl Stationary Phase. Journal Proteome Research, 10, 2104-2012.
10.
Lv, H.T*., Hung, C. S., Chaturvedi, K. S., Hooton, T. M., and Henderson, J.P.* (2011): Development of an integrated metabolomic approach for Infectious Diseases Research. Analyst, 136, 4752-4763. (*Corresponding Author)
11.
Yan, L. Y., Nie, W. N., and Lv, H. T. * (2015) Metabolic Phenotyping of the 耶尔森菌属 High-Pathogenicity Island that Regulates Central 碳 Metabolism. Analyst, 140, 3356-3361. (*Corresponding Author)
12.
Lv, H.T*., Liu, L., Palacios, G. and Chen, X. (2011): Metabolomic Analysis Characterizes Tissue Specific Metabolic Perturbations of the 家鼠属 Induced by Indomethacin. Analyst, 136, 2260-2269. (*Corresponding Author)
13.
Nie, W. N., Lv, Y. N., Yan, L. Y., Guan, T. B., Li, Q., Guo, X. J., Liu, W. H., Feng, M. P., Xu, G., Chen, X., Lv, H. T. * (2015) Discovery and Characterization of Disease Risk Functional Modules and Pathogenic Genes of Coronary Artery Disease. RSC Advances, 5, 26443-26451. (*Corresponding Author)
14.
Lv, Y., Que, Y., Su, Q., Li, Q., and Lu, H*. (2016). 生物信息学 facilitating the use of microarrays to delineate potential miRNA biomarkers in aristolochic acid nephropathy. Oncotarget, doi: 10.18632/oncotarget.10586. (*Corresponding Author)
15.
Su, Q., Guan, T. and Lv, H*. (2016) Siderophore biosynthesis coordinately modulated the virulence associated interactive metabolome of uropathogenic Escherichia coli and human urine. Scientific Reports, 6, 24099; doi: 10.1038/srep24099 (*Corresponding Author
16.
Liu, W. H., Guo, X. J., Li, Q., Xu, G., Feng, M. P., Guan, T. B., Yan, L. Y., Nie, W. N., Parker, T., Lv, H. T. * 质量 Spectrometry Based Molecular Profile Dissects The Complexity of Traditional Chinese Medicine. Anal Methods, 2015, 7, 2902-2912. (*Corresponding Author)
17.
Wang, X.J*., Lv, H.T., Zhang, A. H., Wenjun Sun, Liu, L., Wang, P., Wu, Z.M., Zhou, D. X., Sun, H. * (2013) Metabolite profiling and pathway analysis of acute 肝炎 rats by UPLC-ESI MS combined with pattern recognition methods. Liver International, 34, 759-770.
18.
Wang. X.J.,* Zhang, A.H., Wang, P., Sun, H., Wu, G., Sun, W.J., Lv, H.T., et al. (2013): Metabolomics coupled with proteomics advancing drug discovery towards more agile development of targeted combination therapies. 摩尔 Cell Proteomics. 12, 1226-1238.
19.
Yan, L. Y., Nie, W.N., Parker, T., Upton, Z., Lv, H. T. * (2013) 质量 spectrometry based metabolomics facilitates the discovery of in vivo functional small-molecules with a diversity of biological contexts. Future Medicinal 化学, 5, 1953-1965. (*corresponding author)