宋建国1993年获纽约市立大学生化博士学位，在旧金山加利福尼亚大学做博士后研究。

个人简介

1993年获美国纽约市立大学生化博士学位，在旧金山加州大学做博士后研究。1996年初起在中科院上海生化细胞所任现职。研究方向：细胞分化与凋亡

个人事迹

细胞增殖、凋亡和分化的信号传导机制。主要研究转化生长因子-beta在细胞增殖、凋亡和分化过程中的不同生物学效应及其相关的机制，包括其他因素或信号分子对转化生长因子-beta介导的生物学效应的调节作用。

发表论文：

1.Y Yang, X pan, W Lei, J Wang and J Song Transforming growth factor-beta1 induces epithelial-to-mesenchymal transition and apoptosis via a cell cycle-dependent mechanism （2006）Oncogene 25:7235-44

2.Yanan Yang, Xinchao pan, Weiwei Lei, Jun Wang, Jian Shi, Fuqiang Li and Jianguo Song (2006) Regulation of Transforming Growth Factor-1-Induced Apoptosis and Epithelial-to-Mesenchymal Transition by Protein Kinase A and Signal Transducers and Activators of Transcription 3 Cancer Res 66:8617-24

3.Yiran Zhou, Dongmei Wang, Fuqiang Li, Jian Shi and Jianguo Song Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation （2006） Int J Biochem Cell Biol 38:2151-63.

4，Bo Zhou, Fuqiang Li, Hehua Chen and Jianguo Song The modulation of apoptosis by cyclic AMP involves Akt and epidermal growth factor receptor （2005）Int J Biochem Cell Biol.37:1483-95

5.Sheng Zhao, Yanan Yang and Jianguo Song (2004). 神经酰胺 induces caspase-dependent and -independent apoptosis in A-431 cells. J. Cell. Physiol. 199:47-56.

6.Yanan Yang, Sheng Zhao, and Jianguo Song （2004）. Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor-?1. Int. J. Biochem. Cell Biol. 36:223-34

7.He-Hua Chen, Sheng Zhao and Jian-Guo Song (2003). TGF-?1 suppresses apoptosis via differential regulation of MAP kinases and 神经酰胺 production. Cell 死亡 and Differentiation 10:320-331.

8.Zhao S, Du X, Chen J, Zhou Y, Song J (2002). Secretory phospholipase A2 inhibits epidermal growth factor-induced receptor activation. Exp. Cell Res. 279:354-365.

9.Sheng Zhao, Xiao-Yan Du, Min-Qiang Chai, Jun-Song Chen, Yuan-Chong Zhou and Jian-Guo Song （2002）.Secretory phospholipase A2 induces apoptosis via a mechanism involving 神经酰胺 generation. BBA-摩尔 Biol Cell Lipids. 1581:75-88.

10.Chai Min-Qiang, Chen Jun-Song, Zhao Sheng, Song Jian-Guo (2001). Propranolol increases phosphatidic acid level via phospholipase D activation. Acta Pharmacologica Sinica. 22 22:777-784.

11.Jinhui Liao, Junsong Chen, Minqiang Chai, Sheng Zhao, and Jianguo Song (2001). The involvement of p38 MAPK in transforming growth factor beta 1-induced apoptosis in murine hepatocytes. Cell Research, 11:89-94.

12.Junsong Chen and Jianguo Song (2001). Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells. IUBMB Life, 51:49-56.

13.Binghong Zhou, Junsong Chen, Mingqiang Chai, Sheng Zhao, Jun Lian, Hehua Chen, and Jianguo Song (2000). Activation of phospholipase D activity in transforming growth factor-beta-induced cell growth inhibition. Cell Research, 10:139-149.

14.Jun-Song Chen, Min-Qiang Chai, He-Hua Chen, Sheng Zhao and Jian-Guo Song (2000). Regulation of phospholipase D activity and 神经酰胺 production in daunorubicin-induced apoptosis in A-431 cells. 华晨宝马摩尔 Biol Cell Lipids. 1488:219-232.

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