更新时间：2024-09-21 04:50
张绪穆，1961年10月出生于湖北省鄂州市，是一位著名的配位化合物和金属有机化学家。他曾在武汉大学、中国科学院福建物质结构研究所、加利福尼亚大学-圣地亚哥分校和斯坦福大学学习，并于1992年获得博士学位。他曾在美国宾夕法尼亚州立大学和罗格斯-罗格斯大学担任终身教授，并于2015至2018年间担任南方科技大学化学系讲座教授及系主任。他长期致力于手性药物的绿色、催化不对称合成，以及不对称氢化和手性膦配体两个领域的研究。他还是南方科技大学化学系系主任、绿色催化研究所所长、宾州州立大学教授、坪山生物医药研究院院长等职位的担任者。他于2022年当选为俄罗斯工程院外籍院士，同年当选为中国化学会会士。
张绪穆，1982年毕业于武汉大学化学系，获学士，1992年毕业于斯坦福大学(Stanford)化学系，获博士学位。1992年至1994年在斯坦福大学(Stanford University)化学系做博士后研究。1994年至1999年于宾夕法尼亚州立大学（Penn State University）任助理教授，1999年至2003年于宾州州立大学（Penn State University）任副教授，2003年9月至今于宾州州立大学（Penn State University）任教授。已发表文章90多篇，专利及专利申请42件，曾多次被邀请在国际会议上做报告（正式受邀演讲:210次，其他受邀演讲:75次）。并且是美国凯瑞生化有限公司(Chiral Quest Inc)的创始人和首席技术总监。
2015年，就任南方科技大学化学系系主任。
研究方向：有机化学、金属有机化学、生物无机化学。
近期代表性研究论文：
1.Catalytic Enantioselective Desymmetrization of Meso Cyclic Anhydrides via 铱Catalyzed Hydrogenation. Liu, T. L.; Li, W.; Geng, H. L.; Wang, C. J.; Zhang, X. M. Organic Letters. 2013, 15, 1740.
2.Rhodium-Catalyzed Asymmetric Hydroformylation of 1,1-Disubstituted Allylphthalimides: A Catalytic Route to β3-Amino Acids. Zheng, X.; Cao, B. N.; Liu, T. L.; Zhang, X. M. Advanced Synthesis \u0026 Catalysis. 2013, 355, 679.
3.Cascade Synthesis of Fenpiprane and Related Pharmaceuticals via 铑Catalyzed Hydroaminomethylation. Li, S. K.; Huang, K. X.; Zhang, J. W.; Wu, W. J.; Zhang, X. M. Organic Letters. 2013, 15, 1036.
4.A Novel Triphosphoramidite Ligand for Highly Regioselective Linear Hydroformylation of Terminal and Internal Olefins Chen, C. Y.; Qiao, Y.; Geng, H. L.; Zhang, X. M. Organic Letters. 2013, 15, 1048.
5.铑Catalyzed Enantioselective Hydrogenation of Oxime Acetates.Huang, K. X.; Li, S. K.; Chang, M. X.; Zhang, X. M. Organic Letters. 2013, 15, 484.
6.Highly enantioselective hydrogenation of β,β-disubstituted nitroalkenes. Li, Shengkun; Huang, Kexuan; Cao, Bonan; Zhang, Jiwen; Wu, Wenjun; Zhang, Xumu. Angew. Chem. Int. Edit. 2012, 51, 10679. DOI: 10.1002/anie.201202715
7.New tetraphosphorus ligands for highly linear selective hydroformylation of allyl and vinyl derivatives. Cai, Chaoxian; Yu, Shichao; Cao, Bonan; Zhang, Xumu. Chem. Eur. J. 2012, 18, DOI: 10.1002/chem.201201396.
8.Access to both enantiomers of α-chloro-β-keto esters with a single chiral ligand: highly efficient enantioselective chlorination of cyclic β-keto esters catalyzed by chiral 铜(II) and 锌(II) complexes of a spiro-2,2'-bischroman-based bisoxazoline ligand. Li, Jie; pan, Wei; Wang, Zheng; Zhang, Xumu; Ding, Kuiling. Adv. Synth. Catal. 2012, 354, 1980.
9.Highly enantioselective hydrogenation of β-ketoenamides with the Rh-ZhangPhos catalyst. Huang, Kexuan; Zhang, Xiaowei; Geng, Huiling; Li, Sheng-kun; Zhang, Xumu. ACS Catalysis 2012, 2, 1343.
10.Highly regioselective isomerization-hydroaminomethylation of internal olefins catalyzed by Rh complex with Tetrabi-type 磷 ligands. Liu, Guodu; Huang, Kexuan; Cao, Bonan; Chang, Mingxin; Li, Shengkun; Yu, Shichao; Zhou, Le; Wu, Wenjun; Zhang, Xumu. Org. Lett. 2012, 14, 102.
11.Highly regioselective hydroaminomethylation of terminal olefins to linear amines using Rh complexes with a Tetrabi 磷 ligand. Liu, Guodu; Huang, Kexuan; Cai, Chaoxian; Cao, Bonan; Chang, Mingxin; Wu, Wenjun; Zhang, Xumu. Chem. Eur. J. 2011, 17, 14559.
12.Ruthenium-catalyzed asymmetric hydrogenation of β-keto enamines: an efficient approach to chiral γ-amino alcohols. Geng, Huiling; Zhang, Xiaowei; Chang, Mingxin; Zhou, Le; Wu, Wenjun; Zhang, Xumu. Adv. Synth. Catal. 2011, 353, 3039.
13.Highly regioselective isomerization-hydroformylation of internal olefins catalyzed by 铑/tetraphosphine complexes. Cai, Chaoxian; Yu, Shichao; Liu, Guodu; Zhang, Xiaowei; Zhang, Xumu. Adv. Synth. Catal. 2011, 353, 2665.
14.A highly efficient and enantioselective access to tetrahydroisoquinoline alkaloids: asymmetric hydrogenation with an Iridium catalyst. Chang, Mingxin; Li, Wei; Zhang, Xumu. Angew. Chem. Int. Edit. 2011, 50, 10679.
15.Spiro-2,2'-bichroman-based bisoxazoline (SPANbox) ligands for Zn(II)-catalyzed enantioselective hydroxylation of β-keto esters and 1,3-diester. Li, Jie; Chen, Gang; Wang, Zheng; Zhang, Ruzhou; Zhang, Xumu; Ding, Kuiling. Chem. Sci. 2011, 2, 1141.
16.New synthetic strategy for high-enantiopurity N-protected α-amino ketones and their derivatives by asymmetric hydrogenation. Sun, Tian; Hou, Guohua; Ma, Miaofeng; Zhang, Xumu. Adv. Synth. Catal. 2011, 353, 253.
17.Enantioselective synthesis of optically pure β-amino ketones and γ -aryl amines by Rh-catalyzed asymmetric hydrogenation. Geng, Huiling; Huang, Kexuan; Sun, Tian; Li, Wei; Zhang, Xiaowei; Zhou, Le; Wu, Wenjun; Zhang, Xumu. J. Org. Chem. 2011, 76, 332.
18.Synthesis of enamides via Cu(I)-catalyzed reductive acylation of ketoximes with NaHSO3. Guan, Zheng-Hui; Zhang, Zhi-Yuan; Ren, Zhi-Hui; Wang, Yao-Yu; Zhang, Xumu. J. Org. Chem. 2011, 76, 339.
发明专利：
“New Chiral Ferrocene Phosphines and Their Applications for Asymmetric Catalytic Reactions” X. Zhang, US patent 09/781,083, filed February 9, 2001 and PCT/US01/044.
2."3,3'-Substituted Chiral Biaryl Phosphines and Phosphintes for Asymmetric Catalytic Reactions ” X. Zhang, U. S. Patent, filed November 16, 2001 and PCT Application.
3."New Transition Metal Catalyzed Reactions” A. Lei, X. Zhang, U. S. Provisional Patent, filed March 30, 2001.
4. “New Chiral Phospholanes for Asymmetric Catalysis” X. Zhang, US Patent filed November 6, 2001.
5. “P-chiral Phospholanes and Phosphocyclic compounds and their use in asymmetric catalytic reactions” W. Tang, X. Zhang, US provisional Patent, November 10, 2001.
6. “Asymmetric Reductive Amination of Ketones” X. Zhang, US Provisional Patent, filed October 25, 2002.
7.“P-chiral Phospholanes and Phosphocyclic compounds and their use in asymmetric catalytic reactions” W. Tang, X. Zhang, US Patent, November 10, 2002.
8. “New Chiral 恶唑啉 Ligands for Asymmetric Catalysis” D. Liu, X. Zhang, US Provisional Patent, December 17, 2003.
9.“Asymmetric Hydrogenation of Alpla-amino Carbonyl Compounds” X. Zhang, US Provisional Patent, January 10, 2004
10.“Preparation of chiral cyclic amino acids and derivatives” X. Zhang, W. Tang, US Patent 2004242889.
11.“P-Chiral Phospholanes and Phosphocyclic Compounds and their use in Asymmetric Catalytic Reactionss” X. Zhang, W. Tang, US patent 2004229846.
12. “Catalytic Asymmetric Reductive Amination of Ketones Via Transition Metal Complex Catalyst with Chiral 磷化氢 Ligands” X. Zhang, PCT, 2004, WO 2004058982.
13. “Preparation of Chiral 磷 Cyclic Compounds for Transition Metal-Catalyzed Asymmetric Reactions” X. Zhang, US patent, 2004, 2004072680.
14. “A preparation of aminoalcohols via asymmetric hydrogenation of beta-aminocarbonyl compounds” Zhang,
15.Xumu. US 2005159604 A1 20050721 Patent written in English. Application: US 2005-36157 20050114.
16.“New 恶唑啉 ligands for asymmetric catalysis” Zhang, Xumu; Liu, Duan. U.S. Pat. Appl. Publ. (2005), 2005137403 A1 20050623.
17. “Chelating Tetraphosphorus Ligands with 1,1’-联苯 backbone for transition Metal-catalyzed hydroformylation of Alkenes and Related Reactions” X. Zhang; Y. Yan, PCT Int. Appl. (2007) 2007078859. A2 20070712.
18.新型三齿膦配体及其在线性氢甲酰化及类似反应中的应用（P）. 张绪穆，陈才友. 中国发明专利，CN102875599. 2013-01-16.
Franklin Veatch Graduate Fellowship, 1991, Stanford University
The camille and Henry Dreyfus Foundation New Faculty Award, 1994
都彭 Young Faculty Award, 1996
Office of Naval Research Young Investigator Award, 1996
The Camille and Henry Dreyfus Foundation Teacher-Scholar Award, 1998
The John Simon Guggenheim Foundation Fellow, 2000
The Outstanding Oversea Chinese Young Scientist B, Chinese Academy of Sciences, 2000
The Penn State Faculty Scholar Medal, 2001
The Young Innovation Award of ChiTec (Chinese High Tech) in 化学, 2001
The American Chemical Society Arthur C. Cope Scholar Award, 2002
The SDCA (San Diego Chinese Association) Achievement Award, 2002
Guest The Professor of Shanghai Institute of Organic Chemistry
Guest Professor of 大连市 Institute of Chemical Physics
Guest Professor of Wuhan University
2008年，苏州工业园区第二届科技领军人才
2008年， “江苏省高层次创新创业人才引进计划”引进人才；
2009年，姑苏创新创业领军人才；
2011年, 获2010年度“中国经济十大创新人物”。
师资队伍——张绪穆.南方科技大学——师资队伍.2015-11-16