杨维才 :遗传与发育生物学研究所所长

更新时间:2024-09-20 18:28

杨维才,1964年2月14日出生于九龙坡区,是中原地区科学院院士、发展中国家科学院院士中国科学院大学岗位教授、中国科学院遗传与发育生物学研究所所长。1994年,他获得瓦格宁根大学博士学位。他的研究领域主要集中在植物生殖发育生物学。杨维才在国际一流杂志如Nature、PNAS、Plant Cell等发表了80余篇论文。他的研究成果包括首次分离到了花粉管识别雌性吸引信号的受体蛋白复合体,这一研究被评价为“植物生殖领域的重大突破”。他的研究成果多次获得国家级奖项,如2013年度国家自然科学奖二等奖。2021年11月18日,杨维才当选为中国科学院院士。

人物经历

1984年兰州大学学士。1987年兰州大学硕士。1994年荷兰Wageningen大学博士。1996年美国Cold Spring Harbor实验室博士后,1996-2000年新加坡国立大学分子农业生物学院博士后。2000-2002年新加坡Temasek Life Sciences Laboratory高级科学家,植物生殖和棉花生物技术实验室主任。2003年加入中国科学院遗传与发育生物学研究所,2004年获中国科学院“百人计划”择优支持。2004年国家杰出青年科学基金获得者。2021年8月1日,2021年中国科学院院士增选初步候选人名单公布,杨维才位列其中。2021年11月,入选2021年中国科学院院士增选当选院士名单。

主要成就

研究领域

植物生殖发育的调控机制和进化机制:利用分子遗传学、细胞生物学、基因组学等多学科手段,解析被子植物门精子传递、雌-雄配子互作、双受精和胚胎发生的分子机制,了解植物生殖发育机制的进化规律。

豆科共生固氮机制及其生物技术改良:利用分子遗传学和蛋白组学等手段,解析豆科植物共生固氮微环境构建和维持的分子机制,探索实现非豆科植物固氮的途径。

主要研究

植物雌配子体发育

植物生殖生物学是一门传统学科,传统的研究主要集中于对生殖过程的结构,形态和组织胚胎学描述,由于方法和技术方面的局限,对其分子及遗传机理的研究进展非常缓慢。年来由于Gene/enhancer Trap等系统和激光共聚焦显微技术的应用。植物生殖生物学的研究出现了一线生机。研究组研究的领域主要集中在植物雌配子体的发育方面,如孢原细胞和胚囊中卵细胞,中央细胞的命运决定机理等。通过对配子体突变体的遗传分析和基因克隆,了解植物生殖过程中的基因调控及分子机理。而对一些基本的生物学现象,如细胞极性、细胞命运的确立及受精卵机理等进行更深入的研究,了解植物的生殖过程。

以拟南芥为模式研究水稻基因组功能

在过去20多年,拟南芥作为模式植物在植物分子生物学,遗传学,植物病理学,次生代谢和发育生物学研究方面得到了非常广泛的应用,其6-8周的生活周期,相对小的基因组,自交,易于遗传转化,非常适合大规模繁殖等特点,使其成为首选的模式植物。该研究组希望建立一套以拟南芥为基础的,快速有效的实验系统,来研究农作物如水稻的基因功能,为农业生产提供技术储备。

学术研究

杨维才研究组目前的研究方向是:植物生殖发育的分子遗传学,尤其是雌配子体和胚胎发育过程中细胞极性、细胞命运、细胞分化和雌雄配子细胞相互作用的分子遗传机制,其目标是利用拟南芥、水稻等模式植物来探讨发育生物学的基本问题,并以此为模式研究农作物基因功能。

研究主要集中在以下三个方面:1.生殖细胞分化的分子机理:利用Gene Trap和Enhancer Trap等插入突变系统和激光共聚焦显微技术,通过对配子体突变体的遗传分析和基因克隆,研究植物雌配子体发育的遗传调控机制,了解植物有性生殖过程中的基因调控及分子机理。2.雌雄配子识别与受精卵的分子机理:通过分子遗传学和细胞生物学等多学科手段,研究花粉管定向生长和雌雄生殖细胞识别和相互作用的分子机理。3.农作物重要农艺性状的生物技术改良:利用功能基因组学方法,克隆重要功能基因并研究其作用机理,建立农作物快速有效的遗传转化实验系统,通过转基因技术改良农作物。

论文文献

截至2016年9月7日,杨维才在《自然》等杂志上已发表论文65篇。

1.Luo, Y., Shi, D.-Q., Jia, 大前锋, Bao, Y., Li, H.-J., Yang, W.-C. (2021). Nucleolar histone deacetylases HDT1, HDT2 and HDT3 regulate plant reproductive development, Journal of Genetics and Genomics, https://doi.org/10.1016/j.jgg. 

2.Meng, J. G., Liang, L., Jia, 大前锋, Wang, Y.C., Li, H.J., and Yang, W.C. (2020). Integration of ovular signals and exocytosis of a Ca channel by MLOs in pollen tube guidance. Nature Plants 6: 143–153. 

3.Zhang, M.X., Zhu, S.S., Xu, Y.C., Guo, Y.L., Yang, W.C., and Li, H.J. (2020). Transcriptional repression specifies the central 细胞 for double fertilization. PNAS doi/10.1073/pnas.1909465117. 

4.Tang, J., Jia, P., Xin, P., Chu, J., Shi, D., and Yang, W. (2020). AtTRM61/AtTRM6 complex is a bona fide t核糖核酸 N1-methyladenosine methyltransferase in Arabidopsis. Journal of Experimental 植物学 71: 3024-3036. 

5.Chen, W., Jia, 大前锋, Yang, W.C., and Li, H.J. (2020). 等离子体 membrane H-ATPase-mediated cytosolic proton gradient regulates pollen tube growth. Journal of Integrative Plant Biology 62: 1817-1822. 

6.Li, H.J., and Yang, W.C., (2020). Central cell in flowering plants specication, signaling, and evolution. Frontiers in Plant Science 11:590307. doi: 10.3389/fpls.2020.590307. 

7.Wu, H.M., Xie, D.J., Tang, Z.S., Shi, D.Q., and Yang, W.C. (2020). PINOID regulates floral organ development by modulating auxin transport and interacts with MADS16 in rice. Plant Biotechnology Journal 18: 1778-1795. 

8.Zhao, P., Wang, F., Li, N., Shi, D.Q., and Yang, W.C. (2020). Pentatricopeptide repeat protein MID1 modulates nad2 intron 1 splicing and Arabidopsis development. Scientific Reports 10: 2008. 

9.Iftikhar, A. and Yang, W.C. (2020). The functions of kinesin and kinesin-related proteins in 真核生物 细胞 Adhesion \u0026 Migration 14: 139-152. 

10.Iftikhar, A. and Yang, W.C. (2020). Why are 巴西网球公开赛driven microtubule minus-end directed motors critical to plants? An overview of plant multifunctional kinesins. Functional Plant Biology 47: 524–536. 

11.Shi, C., Luo, P., Du, Y.T., Chen, H., Huang, X., 成姓, T.H., Luo, A., Li, H.J., Yang, W.C., Zhao, P., and Sun, M.X. (2019). Maternal control of suspensor programmed cell 死亡 via gibberellin signaling. Nature Communications 10: 3484. 

12.Long, Y., Xie, D., Zhao, Y., Shi, D., and Yang, W.C. (2019). BICELLULAR POLLEN 1 is a modulator of 脱氧核糖核酸 replication and pollen development in Arabidopsis. New Phytologist 222: 588–603 

13.Meng, J.G., Zhang, M.X., Yang, W.C., and Li, H.J. (2019). TICKET attracts pollen tubes and mediates reproductive isolation between relative 物种 in 十字花科 SCIENCE CHINA Life Sciences 62:1413-1419 

14.Li, Y., Li., H.J., Morgan, C., Bomblies, K., Yang, W., and Qi, B. (2019). Both male and female gametogenesis require a fully functional protein S-acyl transferase 21 in Arabidopsis thaliana. Plant Journal 100:754-767. 

15.Jia, 大前锋, Xue, Y., Li, H.J., and Yang, W.C. (2019). LOT regulates TGN biogenesis and Golgi structure in plants. Plant Signaling \u0026 Behavior 14(3): e1573100. 

16.Jia, P.F., Xue, Y., Li, H.J., and Yang, W.C. (2018). Golgi-localized LOT regulates trans-Golgi network biogenesis and pollen tube growth. PNAS 115: 12307-12312 

17.Li, H.J. and Yang, W.C. (2018). Ligands switch model for pollen-tube integrity and burst. Trend Plant Sci 23: 369-372. 

18.Van Velzena, R., Holmer, R., Bua, F., Rutten, L., van Zeijl, A., Liu, W., Santuari, L., Cao, Q., Sharma, T., Shen, D., Roswanjaya, Y., Wardhani, T.A.K., Kalhor, M.S., Jansen, J., van den Hoogen, J., Güng?r, B., Hartog, M., Hontelez, J., Verver, J., Yang, W.C., Schijlen, E., Repin, R., Schilthuizen, M., Schranz, M.E., Heidstra, R., Miyata, K., Fedorova, E., Kohlen, W., Bisseling, T., Smit, S., and Geurts, R. (2018). Comparative genomics of the nonlegume Parasponia reveals insights into evolution of nitrogen-fixing 根瘤菌 symbioses. PNAS 115: E4700-E4709. 

19.Li, H.J., Meng, J.G., and Yang, W.C. (2018). Multilayered signaling pathways for pollen tube growth and guidance. Plant Reproduction 31, 31-41. 

20.Sun, M.X., Yang, W.C., and Higashiyama, T. (2018). Special issue on plant reproduction research in Asia. Plant Reproduction 31:1-2. 

21.Higashiyama, T.*, and Yang, W.C. (2017). Gametophytic pollen tube guidance: Attractant peptides, gametic controls, and receptors. Plant Physiology 173(1):112-121. 

22.Jia, 大前锋, Li, H.J., and Yang, W.C. (2017). Analysis of 过氧化物酶体 biogenesis in pollen by confocal microscopy and transmission electron microscopy. In Plant Germline Development: Methods and Protocols (Ed. Anja Schmidt), PP. 173-180. Methods in Plant 摩尔ecular Biology 1669. Springer protocols. 

23.Jia, 大前锋, Li, H.J., and Yang, W.C. (2017). Transmission electron microscopy (TEM) to study histology of pollen and pollen tubes. In Plant Germline Development: Methods and Protocols (Ed. Anja Schmidt), PP. 181-189. Methods in Plant Molecular Biology 1669. Springer Protocols. 

24.Yu, T.Y., Shi, D.Q., Jia, 大前锋, Tang, J., Li, H.J., Liu, J., and Yang WC. (2016). The Arabidopsis 捕手 kinase ZAR1 is required for zygote asymmetric division and its daughter 细胞 fate. PLoS Genetics 12(3): e1005933. 

25.Wang, T., Liang, L., Xue, Y., Jia, 大前锋, Chen, W., Zhang, M.X., Wang, Y.C., Li, H.J. and Yang, W. C. (2016). A 捕手 heteromer mediates the male perception of female attractants in plants. Nature 531: 241-244. 

26.Li, H., and Yang W.C. (2016). RLKs orchestrate the signaling in plant male-female interaction. Sci China Life Sci 59: 867-77. 

27.Zhou, Jackie McLean, and Yang, W.C. (2016) 捕手like kinases take center stage in plant biology. Sci China Life Sci 59: 863-6. 

28.Li, H.J., Zhu, S.S., Zhang, M.X., Wang, T., Liang, L., Xue, Y., Shi, D.Q., Liu, J., and Yang, W.C. (2015). Arabidopsis CBP1 is a novel regulator of transcription initiation in central 细胞mediated pollen tube guidance. Plant Cell 27: 2880-2893. 

29.Wang, J.Z., Li, H.J., Han, Z.F., Zhang, H.Q., Wang, T., Lin, G.Z., Chang, J.B., Yang, W.C. and Chai, 约翰·约翰逊 (2015). Allosteric receptor activation by the plant peptide hormone phytosulfokine Nature 525: 265-268.

30.Yan, L.H., Wei, S.W., Wu, Y.R., Hu, 自由欧洲电台, Li, H.J., Yang, W.C., and Xie, Q.* (2015). High-efficiency genome editing in Arabidopsis using YAO promoter-driven CRISPR/Cas9 system. Molecular Plant 8: 1820-1823. 

31.Chen, L.Y., Shi, D.Q., Zhang, W.J., Tang, Z.S., Liu, J., and Yang, W.C. (2015). The Arabidopsis alkaline ceramidase TOD1 is a key turgor 压强 regulator in plant cells. Nature Communications 6: 6030. 

32.Chen, G.H., Sun, J.Y., Liu, M., Liu, J., and Yang, W.C. (2014). SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis. J Genet Genom 41(12), 617-625. 

33.Li, X.R., Li, H.J., Yuan, L., Liu, M., Shi, D.Q., Liu, J., and Yang W.C. (2014). Arabidopsis DAYU/ABERRANT 过氧化物酶体 MORPHOLOGY9 is a key regulator of peroxisome biogenesis and plays critical roles during pollen maturation and germination in planta. Plant 细胞 26: 619-635. 

34.Liu, P., Qi, M., Wang, Y., Chang, M., Liu, C., Sun, M., Yang, W., and Ren, H. (2014). Arabidopsis RAN1 mediates seed development through its parental ratio by affecting the onset of endosperm 细胞ularization. Molecular Plant 7: 1316–1328.

35.Zhu, Y.N., Shi, D.Q., Ruan, M.B., Zhang, L.L., Meng, Z.H., Liu, J., and Yang, WC. (2013). Transcriptome analysis reveals crosstalk of responsive genes to multiple abiotic stresses in cotton (Gossypium hirsutum L.). PLoS ONE 8: e80218. 

36.Cheung, A.Y., Palanivelu, R., Tang, W.H., Xue, H.W., and Yang, W.C. (2013). Pollen and plant reproduction biology: Blooming from east to west. 摩尔ecular Plant 6: 995–997. 

37.Wang, S.Q., Shi, D.Q., Long, Y.P., Liu, J., and Yang, W.C. (2012) 配子体 DEFECTIVE 1, a putative subunit of RNases P/MRP, is essential for female gametogenesis and male competence in Arabidopsis. PLoS One 7: e33595. 

38.Li, H.J. and Yang, W.C. (2012). Emerging role of ER quality control in plant 细胞 signal perception. Protein \u0026 Cell 3: 10-16. 

39.Zhao, Y.T., Wang, M., Fu, S.X., Yang, W.C., Qi, C.K., and Wang, X.J. (2012). Small RNA profiling in two Brassica napus cultivars identifies micro核糖核酸s with oil production and developmental correlated expressions and new small RNA classes. Plant Physiology 158: 813-823. 

40.Liu, W., Kohlen, W., Lillo, A., Op den Camp, R., IVanov, S., Hartog, M., Limpens, E., Jamil, M., Smaczniak, C., Kaufmann, K., Yang, W.C., Hooiveld, G.J.E.J., Charnikhova, T., Bouwmeester, H.J., Bisseling, T., and Geurts, R. (2011). 独脚金内酯 biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2. Plant Cell 23: 3853-3865. 

41.Li H.J., Xue Y., Jia D.J., Wang T., Shi D.Q., Liu J., Cui F., Xie Q., Ye D., and Yang W.C. (2011). POD1 regulates pollen tube guidance in response to micropylar female signalling and acts in early embryo patterning in Arabidopsis. Plant Cell 23: 3288–3302. 

42.Shi, D.Q.* and Yang, W.C.* (2011). Ovule development in Arabidopsis: progress and challenge. Curr Opin Plant Biol 14: 74-80. 

43.Zhao, P., Shi, D.Q., Yang, W.C. (2011). Patterning the embryo in higher plants: Emerging pathways and challenges. Frontiers in Biology 6: 3-11. 

44.Li, H.J., Liu, N.Y., Shi, D.Q., Liu, J., and Yang, W.C. (2010). YAO is a nucleolar WD-40-repeat protein critical for embryogenesis and gametogenesis in Arabidopsis. BMC Plant Biology 10:169. 

45.Liu, M., Shi, D.Q., Yuan, L., Liu J., and Yang, W.C. (2010). SLOW WALKER3, encoding a putative DEAD-box 核糖核酸 解旋酶, is essential for female gametogenesis in Arabidopsis. J Integrat Plant Biol 52: 817-828. 

46.Yang, W.C.*, Shi, D.Q., and Chen, Y.H. (2010). Female 配子体 development in flowering plants. Annu Rev Plant Biol 61: 89–108. 

47.Deng, Y., 越南盾, H., Mu, J., Ren, B., Zheng, B., Ji, Z., Yang, W.C., Liang, Y., and 左姓, J. (2010). Arabidopsis histidine kinase CKI1 acts upstream of HISTIDINE PHOSPHOTRANSFER PROTEINS to regulate female 配子体 development and vegetative growth. Plant Cell 22: 1232–1248. 

48.Shi, D.Q. and Yang, W.C. (2009). Pollen germination and tube growth. In Plant Developmental Biology – Biotechnological Perspectives (eds. ec Pua and M.R. Davey), Springer-Verlag, Heidelberg. Vol. I, pp245-282. 

49.Li, N., Yuan, L., Liu, N., Shi, D., Li, X., Tang, Z., Liu, J., Sundaresan, V., and Yang, W.C. (2009). SLOW WALKER2, a NOC1/MAK21 同系物, is essential for coordinated 细胞 cycle progression during female 配子体 development in Arabidopsis. Plant Physiology 151: 1486-1497. 

50.Ruan, M.B., Zhao, Y.T., Meng, Z.H., Wang, X.J., and Yang W.C. (2009). Conserved mi核糖核酸 analysis in Gossypium hirsutum through small RNA sequencing. Genomics 94: 263-268. 

51.Liu, M., Yuan, L., Liu, N.Y., Shi, D.Q., Liu, J., and Yang, W.C. (2009). GAMETOPHYTIC FACTOR1, involved in pre-mRNA splicing, is essential for megagametogenesis and embryogenesis in Arabidopsis. J Integrat Plant Biol 51: 261-271. 

52.Liu, N.Y., Zhang, 德国采埃孚股份公司, and Yang, W.C. (2008). Isolation of embryo-specific mutants in Arabidopsis: Plant transformation. In Methods in 摩尔ecular Biology: Plant Embryogenesis (ed. M.F. Suarez and P.V. Bozhkov), pp91-100. Humana Press, Totowa, USA. 

53.Liu, N.Y., Zhang, Z.F., and Yang, W.C. (2008). Isolation of embryo-specific mutants in Arabidopsis: Genetic and phenotypic analysis. In Methods in 摩尔ecular Biology: Plant Embryogenesis (ed. M.F. Suarez and P.V. Bozhkov), pp101-109. Humana Press, Totowa, USA. 

54.Pu, L., Li, Q., Fan, X.P., Yang, W.C., and Xue, Y.B. (2008). A R2R3 MYB transcription factor GhMYB109 is required for cotton fiber development. Genetics 180: 811-820. 

55.Wang, F., Shi, D.Q., Liu, J., and Yang, W.C. (2008). Novel nuclear protein ALC-INTERACTING PROTEIN1 is expressed in vascular and mesocarp 细胞s in Arabidopsis. J Integrat Plant Biol 50: 918-927. 

56.Liu, J., Zhang, Y., Qin, G., Tsuge, T., Sakaguchi, N., Luo, G., Sun, K., Shi, D., Aki, S., Zheng, N., Aoyama, T., Oka, A., Yang, W.C., Umeda, M., Xie, Q., Gu, H., and Qu L.J. (2008). Targeted degradation of the cyclin-dependent kinase inhibitor ICK4/KRP6 by RING-type E3 ligases is essential for mitotic 细胞 cycle progression during Arabidopsis gametogenesis. Plant Cell 20: 1538-1554. 

57.Chen, Y.H., Li, H.J., Shi, D.Q., Yuan, L., Liu, J., Sreenivasan, R., Baskar, R., Grossniklaus, U., and Yang, W.C. (2007). The central cell plays a critical role for pollen tube guidance in Arabidopsis. Plant Cell 19: 3563-3577. 

58.Escobar-Restrepo, Jackie McLean, Huck, N., Kessler, S., Gagliardini, V., Gheyselinck, J., Yang, W.C., and Grossniklaus, U. (2007). The FERONIA 捕手like kinase mediates male-female interactions during pollen tube reception. Science 317: 656-660.

59.Meng, Z.H., Liang, A.H., and Yang, W.C. (2007). Effects of hygromycin on cotton cultures and its application in 农杆菌属mediated cotton transformation. In Vitro Cell Dev Biol-Plant 43: 111-118. 

60.Song, X.F., Yang, C.Y., Liu, J., and Yang, W.C. (2006). RPA, a Class II ARFGAP protein, activates ARF1 and U5 and plays a role in root hair development in Arabidopsis. Plant Physiology 141: 966-976. 

61.Ding, Y.H., Liu, N.Y., Tang, Z.S., Liu, J., and Yang, W.C. (2006). Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis and encodes a novel nuclear 无规共聚聚丙烯 motif protein that interacts with RNA polymerase II subunit III. Plant Cell 18: 815-830. 

62.Chen, Y.H., Wu, X.M., Ling, H.Q., and Yang, W.C. (2006). Transgenic expression of DwMYB2 impairs iron transport from root to shoot in Arabidopsis thaliana. Cell Research 16: 830-840. 

63.Yang, W.C. (2005). Female 配子体 development, In Handbook of Seed Science and Technology (ed. Basra, A.S.), pp.27-62. The Haworth Press, Inc. New York. 

64.Yang, sl, Jiang, L., Puah, 计算机科学, Xie, L.F., Zhang, X.Q., Chen, L.Q., Yang, W.C., and Ye, D. (2005). Overexpression of TAPETUM ETERMINANT1 alters the cell fates in the Arabidopsis carpel and tapetum via genetic interaction with EXCESS MICROSPOROCYTES1/EXTRA SPOROGENOUS CELLS. Plant Physiology 139: 186-191. 

65.Shi, D.Q., Liu, J., Xiang, Y.H., Ye, D., Sundaresan, V., and Yang, W.C. (2005). SLOW WALKER1, essential for gametogenesis in Arabidopsis, encodes a WD40 protein involved in 18S ribosomal RNA biogenesis. Plant Cell 17: 2340-2354. 

66.Li, X.B., Fan, X.P., Wang, X.L., Cai, L., and Yang, W.C. (2005). The cotton ACTIN1 gene is functionally expressed in fibers and participates in fiber elongation. Plant Cell 17: 859-875. 

67.Jiang, J., Yang, sl, Xie, L.F., Puah, 计算机科学, Zhang, X.Q., Yang, W.C., Sundaresan, V., and Ye, D. (2005). VANGUARD1 encodes a 果胶 methylesterase that enhances pollen tube growth in the Arabidopsis style and transmitting tract. Plant Cell 17: 584-596. 

68.Rotman, N., Durbarry, A., Wardle, A., Yang, W.C., Chaboud, A., Faure, J.-F., Berger, F., and Twell, D. (2005). A novel class of MYB factors controls sperm-cell formation in plants. Current Biology 15: 244-248. 

69.Yang, sl, Xie, L.F., Mao, 赫兹, Puah, 计算机科学, Yang, W.C., Lixi Jiang, L.X., Sundaresan, V., and Ye, D. (2003). The TAPETUM DETERMINANT 1 gene is required for cell specialization in the Arabidopsis anther. Plant Cell 15: 2792-2804. 

70.Wu, X.M. Lim, S.H., and Yang, W.C. (2003). Characterization, expression and phylogenetic study of R2R3-MYB genes in orchid. Plant 摩尔 Biol 51: 959-972. 

71.Compaan, B., Yang. W.C., Bisseling, T., and Franssen, H. (2001). ENOD40 expression in the pericycle precedes cortical cell division in 根瘤菌legume interaction and the highly conserved internal region of the gene does not encode a peptide. Plant \u0026 Soil 230: 1-8. 

72.Yang, W.C., and Sundaresan, V. (2000). Genetics of 配子体 biogenesis in Arabidopsis. Curr Opin Plant Biol 3: 53-57. 

73.Yang, W.C., Ye, D., Xu, J., and Sundaresan, V. (1999). The SPOROCYTELESS gene of Arabidopsis is required for sporogenesis and encodes a novel protein. Genes \u0026 Development 13: 2108-2117. 

74.Yang, W.C. (1999). 摩尔ecular mechanism of root nodule formation. In Molecular Mechanisms of Plant Development (ed. Z.H. Xu and C.M. Liu) (in Chinese). Science Press, Beijing, China 

75.Kumaran, M., Ye, D., Yang, W.C., and Sundaresan, V. (1999). 摩尔ecular cloning of abnormal floral organs: a gene required for flower development in Arabidopsis. Sex Plant Reprod 12: 118-122. 

76.Parinov, S., Sevugan, M., Ye, D., Yang, W.C., Kumaran, M., and Sundaresan, V. (1999). Analysis of flanking sequences from Dissociation insertion lines: a database for reverse genetics in Arabidopsis. Plant Cell 11: 1-9. 

77.Heidstra, R., Yang, W.C., Yalcin, Y., Peck, S., Emons, A., Van Kammen, A., and Bisseling, T. (1997). 乙烯 provides positional information on cortical cell division but is not involved in Nod factor-induced root hair tip growth in 根瘤菌legume interaction. Development 124: 1781-1787. 

78.Meskiene, I., Yang, W.C., De Blank, C., Bogre, L., Zwerger, K., Brandstotter, M., Mattauch, M., Bisseling, T., and Hirt, H. (1996). Cell cycle regulation during nodule development. In Biological Fixation of for Ecology and Sustainable Agriculture/NATO ASI series, Series G, Ecological Sciences, 39:63-65. 

79.Christiansen, H., Hansen, A.C., Vijn, I., Pallisgaard, N., Larsen, K., Yang W.C., Bisseling, T., Marcker, K.A., and Jensen, E.O. (1996). A novel type of 脱氧核糖核酸binding protein interacts with a conserved sequence in an early nodulin ENOD12 助催化剂 Plant 摩尔 Biol 32: 809-821. 

80.Vijn, I., Yang W.C., Pallisgaard, N., Ostergaard Jensen, E., Van Kammen, A., and Bisseling, T. (1995). VsENOD5, VsENOD12 and VsENOD40 expression during 根瘤菌induced nodule formation on Vicia sativa roots. Plant 摩尔 Biol 28: 1111-1119. 

81.Vijn, I., Martinez-Abarca, F., Yang, W.C., das neves, L., van Brussel, A., van Kammen, A., and Bisseling, T. (1995). Early nodulin gene expression during Nod factor-induced processes in Vicia sativa. Plant Journal 8: 111-119. 

82.Bialek, U., Skorupska, A., Yang, W.C., Bisseling, T., and Van Lammeren, AAM (1995). Disturbed gene expression and bacteroid development in Trifolium pratense root nodules induced by a Tn5 mutant of 根瘤菌 leguminosarum bv. trifolii defective in exopolysaccharide synthesis. Planta 197: 184-192. 

83.Brito, B., Palacios, J.M., Imperial, J., Ruiz-Argueso, T., Yang, W.C., Bisseling, T., Schmidt, H., Kerl, V., Bauer, T., Kokotek, W., and Lotz, W. (1995). Temporal and spatial 世界斯诺克中国公开赛expression of hydrogenase and nitrogenase genes from 根瘤菌 leguminosarum 细菌性阴道病 viciae in pea (豌豆属 sativum L.) root nodules. Mol Plant-Micobe Interact 8: 235-240. 

84.Mylona, P., Moerman, M., Yang, W.C., Gloudemans, T., De Kerkhove, J., Van Kammen, A., Bisseling, T., and Franssen, H.J. (1994). The root epidermis specific pea gene RH2 is homologous to a pathogen related gene. Plant Mol Biol 26: 39-50. 

85.Matvieko, M., Van de Sande, Yang, W.C., K., Van Kammen, A., Bisseling, T., and Franssen, H. (1994). Comparison of soybean and pea ENOD40 cDNA 克隆s representing genes expressed during both early and late stages of nodule development. Plant Mol Biol 26: 487-493. 

86.Yang, W.C., De Blank, C., Meskiene, I., Hirt, H., Bakker, J., Van Kammen, A., Franssen, H., and Bisseling, T. (1994). 根瘤菌 nod factors reactivate the cell cycle during infection and nodule primordium formation, but the cycle is only completed in primordium formation. Plant Cell 6: 1415-1426. 

87.De Maagd, 类风湿性关节炎, Yang, W.C., Goosen-de Roo, L., Mulders, I.H.M., Roest, H.P., Spaink, H.P., Bisseling, T., and Lugtenberg, B.约翰·约翰逊 (1994). Down-regulation of expression of the 根瘤菌 leguminosarum outer membrane protein gene ropA occurs abruptly in interzone II-III of pea nodules and can be uncoupled from nif gene activation. Mol Plant-Microbe Interact 7: 276-281. 

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社会任职

1.Multinational Arabidopsis Steering Committee中国区代表(2006-2016)

2.International Association of Sexual Plant Reproduction Research (IASPRR), Board member (2004-2006)

3.中国遗传学会常务理事 (2008-2018年)、副理事长/兼秘书长(2019-2024年)

4.中国细胞生物学会理事 (2007-2011年)

5.《植物学报》副主编 (2008-2014年)

6.Journal of Integrative Plant Biology副主编 (2008-2016年)

7.Journal of Genetics and Genomics 副主编 (2010年-)

8.Journal of Plant Biology编委 (2012-2016年)

9.Plant Signaling and Behavior编委 (2008-2016年)

10.Cell Research编委 (2006-2010年)

11.Molecular Plant编委 (2007年- )

12.Sexual Plant Reproduction编委 (2011-2012年)

13.Plant Reproduction编委 (2013年-)

14.Scientific Reports编委 (2011年-)

15.Science in China: Life Science编委 (2008年-)

16.aBiotech编委(2019年-)

17.中国作物学会第十一届理事会理事、常务理事、副理事长(2019-2024)

18.中国科学院遗传与发育生物学研究所生物安全委员会主任

19.中国植物学会植物结构与生殖生物学专业委员会副主任

人才培养

讲授课程

2022年12月16日,杨维才在中国科学院遗传与发育生物学研究所讲授博士学位课程《遗传与发育》第十三章“植物早期发育与形态建成”。

培养成果

杨维才培养的学生有西北农林科技大学教授袁黎,中国科学院遗传与发育生物学研究所研究员李红菊,福建农林大学教授陈立余,南通大学教授陈艳红,河北农业大学教授李娜等。

获得荣誉

2004年,获国家中华人民共和国国家自然科学基金委员会“国家杰出青年基金”资助。

2007年,获中国科学院“优秀研究生指导教师“奖;获准享受政府特殊津贴;人事部“新世纪百千万人才工程国家级人才人选”。

2008年,获中国科学院“宝洁优秀研究生导师”奖。

2008年,获International Association of Sexual Plant Reproduction Research, Outstanding Service Award。

2013年,国家自然科学奖(二等),”被子植物门有性生殖的分子机理研究。

2016年,获“全国优秀科技工作者”(中国科学技术协会);入选“科学中国人(2015)年度人物”;获中国科学院优秀教师奖。

2018年,获中国科学院优秀教师奖。

2021年8月1日,入选2021年中国科学院院士增选初步候选人名单。

2021年11月,入选2021年中国科学院院士增选当选院士名单。

社会评价

杨维才——中国科学院遗传与发育生物学研究所(简称“遗传发育所”)所长。长期以来,他投身于植物生殖发育调控机理研究,在Nature等杂志上发表论文65篇,主持的“被子植物门有性生殖的分子机理研究”获2013年度国家自然科学奖二等奖,是该领域具有重要国际影响的学者。在科学中国人(2015)年度人物评选中,杨维才因其突出贡献当选为生命科学领域年度人物。

2016年,他的团队对雌雄配子识别分子机制的系列研究取得了具有重大国际影响的突破,分离了花粉管识别胚囊雌性吸引信号的受体蛋白复合体并揭示其激活的分子机制。该研究通过基因工程手段建立利用生殖关键基因打破生殖隔离的方法,为克服杂交育种中杂交不亲和性提供了重要理论依据。

参考资料

杨维才.中国科学院遗传与发育生物学研究所.2024-08-22

关于公布2021年中国科学院院士增选初步候选人名单的公告.中国科学院.2021-12-04

关于公布2021年中国科学院院士增选当选院士名单的公告.中国科学院网.2021-11-18

杨维才.中国科学院遗传与发育生物学研究所.2021-12-04

生命科学学院“高端学术论坛”之五十九~六十二.广州大学新闻网.2021-12-04

杨维才:平常心态做人 世界水准行研.科学中国人官方网站.2024-08-23

第十一届理事会(2019—2024).中国作物学会.2024-08-24

专家介绍-杨维才.中国计量测试学会生物计量专业委员会.2024-08-24

遗传发育所博士学位课--遗传与发育课表(2022).中国科学院遗传与发育生物学研究所.2024-08-22

关于公布2021年中国科学院院士增选初步候选人名单的公告.中国科学院.2021-08-28

科学中国人|科学中国人官方网站|科学中国人杂志社.科学中国人杂志社.2021-10-03

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