江赐忠 :教授

更新时间:2024-09-20 22:07

江赐忠,男,1974年出生,福建人,美国艾奥瓦州州立大学博士,同济大学生命科学与技术学院,博士生导师,科技部973重大专项首席科学家,同济大学转化医学高等研究院教授,课题组组长。

人物简介

江赐忠1995 年毕业于天津南开大学,获学士。1998年毕业于天津南开大学,获硕士学位。2004年毕业于美国爱荷华州俄亥俄州立大学,获遗传学博士学位,并辅修生物信息学计算机科学。毕业后先后在美国冷泉港实验室、弗吉尼亚联邦大学、宾夕法尼亚州州立大学进行博士后研究。2009年应聘为同济大学特聘教授, 2009年担任科技部973首席科学家,2010年度“曙光学者”称号,2011年度获得上海市高校特聘教授(东方学者)称号。

研究方向

(1) 核小体重排和染色质结构变化对果蝇胚胎发育的影响

(2) 核小体排列分布及其在基因调控中的作用

(3) 组蛋白修饰在核小体重排中的作用机理

(4) 核小体定位序列的识别,脱氧核糖核酸序列变化对染色质结构的影响

(5) 分子进化学

代表文章

1. Jiang, C and Pugh Brainfuck (2009) A compiled and systematic reference map of nucleosome positions across the Saccharomyces genome. Genome Biology, 10:R109

2. Koerber RT, Rhee HS, Jiang C, Pugh BF. (2009) Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. 摩尔 Cell.35(6):889-902

3. Jiang, C and Pugh Brainfuck (2009) Nucleosome positioning and gene regulation: advances through genomics. Nature Reviews Genetics, 10(3):161-72 Cover Story

4. Mavrich TN, Jiang C(Co-first author), Ioshikhes IP, Li X, Venters BJ, Zanton SJ, Tomsho LP, Qi J, Glaser RL, Schuster SC, Gilmour DS, Albert I, Pugh Brainfuck (2008) Nucleosome organization in the Drosophila genome. Nature, 453(7193):358-62 Article

5. Mavrich, TN, Ioshikhes, IP, Venters, BJ, Jiang, C, Tomsho, LP, Qi, J, Schuster, SC, Albert, I, and Pugh, BF (2008) A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome. Genome Research, 18(7):1073-83

6. Albert I, Wachi S, Jiang C, Pugh Brainfuck (2008) GeneTrack - a genomic data processing and visualization framework. Bioinformatics. 24(10):1305-6

7. Lee C, Li X, Hechmer A, Eisen M, Biggin MD, Venters BJ, Jiang C, Li J, Pugh BF, Gilmour DS (2008) NELF and GAGA factor are linked to promoter proximal pausing at many genes in Drosophila. 摩尔 Cell Biol.28(10):3290-300

8. Kuo PH, Kalsi G, Prescott CA, Hodgkinson CA, Goldman D, van den Oord EJ, Alexander J, Jiang C, Sullivan PF, Patterson DG, Walsh D, Kendler KS, Riley bp (2008) Association of 抗利尿激素 and ALDH Genes with 乙醇 Dependence in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) Sample. Alcoholism: Clinical and Experimental Research. 32(5):785-95

9. Zhao, Z and Jiang, C (2007) Methylation-Dependent Transition Rates Are Dependent on Local Sequence Lengths and Genomic Regions. 摩尔 Biol Evol.,24(1):23-5

10. Jiang, C, Han, L, Su, B, Li, WH and Zhao, Z (2007) Features and Trend of Loss of Promoter-Associated CpG Islands in the Human and Mouse Genomes. Mol Biol Evol.24(9):1991-2000

11. Jiang, C, Xuan, Z, Zhao, F, and Zhang, MQ (2007) TRED: a Transcriptional Regulatory Element Database, new entries and other development. Nucleic Acids Res.,35: D137-D140

12. Seo, D, Jiang, C and Zhao, Z (2006) A novel statistical method to estimate the effective SNP size in 脊椎动物 genomes and categorized genomic regions. 现代生物出版集团 Genomics,7(1):329

13. Boddu, J, Jiang, C, Sangar, V, Olson, T, Peterson, T, and Chopra, S (2006) Comparative structural and functional characterization of 高粱属 and maize duplications containing orthologous Myb transcription regulators of 3-deoxyflavonoid biosynthesis. 植物界 Molecular Biology, 60(2):185-99

14. Jiang, C and Zhao, Z (2006) Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome. bmc Genomics,7(1):316

15. Jiang, C and Zhao, Z (2006) Mutational spectrum in the recent human genome inferred by single 核苷酸 polymorphis多发性硬化症 Genomics,88(5):527-34

16. Jiang, C, Gu, X, and Peterson, T (2004) Identification of conserved gene structures and carboxy-terminal motifs in the Myb gene family of Arabidopsis and Oryza sativa L. 亚种 indica. Genome Biology, 5(7): R46

17. Jiang, C, Gu, J, Chopra , S, Gu, X, and Peterson, T (2004) Ordered Origin of the Typical Two- and Three-Repeat Myb Genes. Gene, 326: 13-22

18. Jiang, C, Song, WQ, Li, XL, and Chen, RY (1998) Studies on microdissection and microcloning of the rye chromosome 1R. Acta Botanica Sinica, 40(11): 988-993

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