更新时间：2024-09-21 00:19
谭斌博士。 2005年硕士毕业于厦门大学化学化工学院。同年去新加坡留学，在新加坡南洋理工大学化学与生物化学系钟国富教授的指导下从事新型手性有机催化剂的设计合成及不对称domino反应的研究并于2010 年3月取得博士学位。2010年3月至2012 年9月，有幸在有机小分子催化领域的发源地之一美国The Scripps Research Institute，师从Barbas教授继续在此领域从事博士后研究。与此同时得到碳氢键活化大师Yu Jin-Quan教授的指点。 2012年9月，以准聘（Tenure-Track）副教授身份加入南方科技大学化学系。2018年1月晋升为终身正教授。
◆ 2010.3年至2012.9年，博士后, 美国斯克普斯研究所（The Scripps Research Institute）。
◆ 2012年9月至今，副教授，南方科技大学化学系。
◆ 2010年，获得新加坡南洋理工大学哲学博士学位 (有机化学)。
◆ 2005年，获得厦门大学理学硕士学位 (有机化学)。
◆ 核心骨架结构导向的有机催化不对称合成。
◆ 现代催化体系和绿色合成全新方法的开发。
◆ 金属与有机催化组成的协同催化体系拓展。
◆ 手性药物的开发和天然产物的策略全合成。
代表性研究成果：（独立工作以后从2013年7月至今）
24. Brønsted acid-catalysed enantioselective construction of axially chiral aryl喹唑啉酮Yong-Bin Wang, Sheng-Cai Zheng, Yu-Mei Hu \u0026 Bin Tan. 2017, , 15489
23. Organocatalytic atropselective synthesis of axially chiral styrenes. Sheng-Cai Zheng, San Wu, Qinghai Zhou, Lung Wa Chung, Liu Ye \u0026 Bin Tan. 2017, , 15238.
22. Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal–Knorr Reaction. Lei Zhang, Jian Zhang, Ji Ma, Dao-Juan Cheng, and Bin Tan*. , 2017, 139 (5), 1714–1717.
21. Phosphoric Acid-Catalyzed Asymmetric Synthesis of SPINOL Derivatives. Shaoyu Li, Ji-Wei Zhang, Xian-Lin Li, Dao-Juan Cheng, and Bin Tan*.J. Am. Chem. Soc., 2016, 138 (50), 16561–16566.
20.Construction of Tropane Derivatives by the Organocatalytic Asymmetric Dearomatization of Isoquinolines.JinHui Xu, Sheng-Cai Zheng, Ji-Wei Zhang, Xin-Yuan Liu, and Bin Tan*. 2016, 55, 11834–11839.
19. Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction.Ji-Wei Zhang,Jin-Hui Xu,Dao-Juan Cheng,Chuan Shi,Xin-Yuan Liu* \u0026Bin Tan*.Nature Communications., 2016, 7, 10677.
18. Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2-Naphthols. Ye-Hui Chen,Dao-Juan Cheng,Jian Zhang,Yong Wang,Xin-Yuan Liu*, andBin Tan*.J. Am. Chem. Soc., 2015,137(48), 15062–15065.
17.Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction. Jian Zhang,Shao-Xia Lin,Dao-Juan Cheng,Xin-Yuan Liu*, andBin Tan*.J. Am. Chem. Soc., 2015,137(44),14039–14042.
16. Asymmetric Construction of Spirooxindoles by Organocatalytic Multicomponent Reactions Using Diazooxindoles. Ming-Yue Wu,Wei-Wei He, Xin-Yuan Liu*, Bin Tan*.Angew.chem. Int. Ed.2015,54,9409–9413.
15. Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan*. Angew. Chem. Int. Ed.2014,53, 3684–3687.
14. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* Xin-Yuan Liu*, Asymmetric Synthesis of Axially Chiral Isoquinolones: 镍Catalyzed Denitrogenative Transannulation. Angew. Chem. Int. Ed. 2015, 54, DOI: 10.1002/anie. 201503207.
13. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* Xin-Yuan Liu*, Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted 碳 Stereocenter. Angew. Chem. Int. Ed. 2015, 54, 7847.
12. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* Xin-Yuan Liu*，磷化氢Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles. Angew. Chem. Int. Ed. 2015, 54, 4041.
11. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan*,and Xin-Yuan Liu* “Enantioselective C-H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene” Angew. Chem. Int. Ed. 2014, 53, 11890.
10. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu*, Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluorom乙酯 γ-Lactam and Spiro苯并呋喃one-lactam. ACS Catal. 2015, 5, 2826.
9. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes. Org. Lett. 2015, 17, 1589-1592.
8. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form 碳Heteroatom/Carbon Bonds. Chem. Eur. J. 2015, 21, 6718.
7. Lei Li, Jing-Yao Guo, Su Chen, Tao Wang, Bin Tan* and Xin-Yuan Liu* “Amide Groups Switch Selectivity: C-H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation” Org. Lett., 2014, 16, 6032.
6. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan* and Xin-Yuan Liu* “铜Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles” J. Org. Chem. 2014, 79, 7084.
5. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu* and Bin Tan* “In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles” Org. Lett. 2014, 16, 2192.
4. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu* “Direct Access to α-CF3-enones via Efficient 铜Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement” Org. Lett. 2014, 16, 1000.
3. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan* and Xin-Yuan Liu.* “Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles” Org. Lett. 2014, 16, 504.
2. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu*. “Efficient 铜Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse 氮Based Nucleophiles” Chem. Eur. J. 2014, 20, 1332.
1. Dao-Juan Cheng, Yoshihiro Ishihara, Bin Tan* and Carlos F. Barbas, III* “Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies”.ACS Catal. 2014, 4, 743
代表性研究成果：（独立工作以前，只列第一作者，所有文章的影响因子都大于5.5）
1.Tan. B.; Toda N; Barbas III, C. F. Organocatalytic Amidation and Esterification of Aldehydes with Activating Reagents by a Cross-coupling Strategy. Angew. Chem. Int. Ed. 2012, 51, 12538-12541.
2.Tan. B.; Hernández-Torres, G.; Barbas III, C. F. Rational 设计 Enables Amide Nucleophiles for Organocatalytic Asymmetric Michael Reactions. Angew. Chem. Int. Ed. 2012, 51, 5381-5385.
3.Tan, B.; Zeng, X.; Leong, W. W. Y.; Shi, Z.; Barbas III, C.F.; Zhong, G. Core Structure-Based 设计 of a Novel Organocatalytic [3+2] Cycloaddition: Highly efficient and Stereocontrolled Synthesis of Spirocyclic Oxindoles. Chem. Eur. J. 2012, 18, 63-67.
4.Tan, B.; Candeias, N.; Barbas III, 铬 Construction of Bispirooxindoles Containing three Quaternary Stereocentres in a Cascade Using a Single Multifunctional Organocatalyst. Nature Chem. 2011, 3, 473-477.
5.Tan B.; Hernández-Torres, G.; Barbas III, C.F. J. Highly Efficient 氢Bonding Catalysis of the Diels-Alder Reaction of 3-Vinylindoles and Methyleneindolinones Provides Carbazolespirooxindole Skeleton Am. Chem. Soc. 2011, 131, 12354-12358.
6.Tan, B.; Candeias, N.; Barbas III, C.F. J. Core-Structure-Motivated 设计 of a 磷化氢Catalyzed [3+2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles. Am. Chem. Soc. 2011, 131, 4672-4675.
7.Tan, B.; Zeng, X.; Chua, P. J.; Zhong, G. Rational 设计 of Domino Michael-Henry Reaction: Direct Construction of Bicyclo[3.2.1]辛烷 Skeletons with Four Stereogeric Centers. Org. Lett. 2010, 12, 2682-2685.
8.Tan, B.; Zhu, D.; Zhang, L.; Dai, L.; Chua, P. J.; Shi, Z.; Zeng, X; Zhong, G. 液态水 More than Just a Green Solvent: A Stereoselective One-Pot Access to All Chiral Tetrahydronaphthalenes in Aqueous Media. Chem. Eur. J. 2010, 16, 3842-3848.
9.Tan, B.; Shi. Z.; Chua, P. J.; Li, Y.; Zhong, G. Unusual Domino Michael/Aldol Condensation Reactions Employing Oximes as N-Selective Nucleophiles: Synthesis of N-Hydroxy吡咯s. Angew. Chem. Int. Ed. 2009, 48, 758-761.
10.Tan, B.; Zhang, X.; Chua, P. J.; Zhong, G. Recyclable organocatalysis: highly enantioselective Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins (Cover Article). Chem. Commun. 2009, 779-781
11.Tan, B.; Zeng, X.; Lu, Y.; Chua, P. J.; Zhong, G. Rational 设计 of Organocatalyst: Highly Stereoselective Michael Addition of Cyclic Ketones to Nitroolefins. Org. Lett. 2009, 11, 1931-1933.
12.Tan, B.; Chua, P. J.; Zeng, X.; Lu, M.; Zhong, G. A Highly Diastereo- and Enantioselective Synthesis of Multisubstituted Cyclopentanes with Four Chiral Carbons by the Organocatalytic Domino 迈克尔·杰克逊Henry Reaction. Org. Lett. 2008, 10, 3489-3492.
13.Tan, B.; Shi, Z.; Chua, P. J.; Zhong, G. Control of Four Stereocenters in an Organocatalytic Domino Double Michael Reaction: Efficient Synthesis of Multisubstituted Cyclopentanes. Org. Lett. 2008, 10, 3425-3428.
14.Tan, B.; Chua, P. J.; Li, Y.; Zhong, G. Organocatalytic Asymmetric Tandem Michael-Henry Reactions: A Highly Stereoselective Synthesis of Multifunctionalized Cyclohexanes with Two Quaternary Stereocenters. Org. Lett. 2008, 10, 2437-2440.
1.Zhong, G.; Tan, B.; Zhang, X.; Chua, P. J. Process for highly enantioselective Michael addition of 1,3-diaryl-1,3-propanedione to nitroolefins using using cinchona alkaloids as recyclable organocatalysts. U.S. Pat. Appl. Publ. (2012), US 20120004424 A1 20120105.
2.Zhong, G,; Tan, B.; Shi, Z. Chua, P. J. Process of forming pyrrole compounds. U.S. Pat. Appl. Publ. (2011), US 20110124881 A1 20110526.
3.Zhong, G,;Tan, B.; Chua, P. J.; Shi, Z. Process for preparation of chiral cycloalkane derivatives by asymmetric cyclization. U.S. Pat. Appl. Publ. (2010), US 20100298576 A1 20101125.
4.Zhong, G.; Lu, M.; Zhu, D.; Lu, Y.; Hou, Y.; Tan, B. Processes for enantioselective preparation of an aminoxy compound and an 1,2-oxazine compound. U.S. Pat. APPL Publ. (2011), US 20110224429 A1 20110915.
◆ 2013年，深圳市海外高层次人才“孔雀计划”入选者。
◆ 2009年，国家优秀自费留学生奖学金。
南科大师资队伍.南方科技大学.2014-02-11