更新时间：2024-09-21 13:04
郑毅男，男，1945年出生，汉族，中共党员，中国民主同盟盟员，吉林省第九届人大代表，留日医学博士，吉林农业大学中药材学院教授，农学与耕作学学科博士生导师。吉林省特产学会副理事长，中国人参学会常务理事，中国植物学会药用植物及中药专业委员会委员，国家中医药管理局“中药学”重点学科学科带头人。
先后为硕士、博士研究生主讲《中药炮制学》、《天然药物化学》等多门课程；在科学研究上，一直从事中药方面研究，尤其在人参加工理论方面颇有见地，发现红参加工是遵循梅拉德反应的原理；同时发现人参中具有广泛生理活性的AFG，是首次自人参中分离得到的新天然化合物，其含量超过人参总皂苷，为人参的评价和临床应用提供了新的理论依据。曾先后主持国家、部省级科研项目15项，获得多项科研成果，其中获省科学技术进步二等奖1项；获长春市科技进步二等奖1项，其中“人参非皂抗衰老保健品开发研究”经鉴定达到国际领先，已经申请“人参次级皂苷脂肪酸合成及其应用”、“人参果提取物的制备方法及治疗糖尿病的药物用途”等发明专利2项；多年来，发表学术论文100余篇，其中SCI收录9篇；出版科技著作2部。目前主要从事保健食品和癌症辅助治疗药物的研究，现正主持教育部、四川省科学技术厅以及横向联合等3项在研基金项目。
Zheng Yi-nan, Zhang Jing, Han Li-kun, Sekiya Keizo, Kimura Yoshiyuki, Okuda Hiromichi. Effects of compounds in leaves of Salix matsudana on arachidonic acid 新陈代谢 Yakugaku Zasshi. 2005, 125(12):1005-1008.
[2]Han Li-kun, Nose Rumiko, Li Wei, Gong Xiao-jie, Zheng Yi-nan, Yoshikawa Masayuki, Koike Kazuo, Nikaido T amotsu, Okuda Hiromichi, Kimura Yoshi矶谷有希 Reduction of fat storage in mice fed a high-fat diet long term by treatment with saponins prepared from Kochia 野甘草属 fruit. Phytother Res, 2006, 20(10):877-882.
Xiang Li, Zheng Yinan, Isabel Sattler and Wenhan Lin，Griseusin C, and novel quinone derivative from a marine-derived fungus 青霉菌 sp. Arch Pharm Res. 2006, 29(11): 942-945.
Li Xiang, Zheng Yi-nan Lin Wen-han, Sattler Isabel. A New Vriginae Butanolide from 链霉菌属 sp. Chin Chem Lett, 2006, 17(11):1466-1468.
Li Xiang; Li Min-yi; Zheng Yi-nan; Lin Wen-han. Structure Elucidation of Taraxerone Isolated from Mangrove Excoecaria Agallocha. Chinese Journal of Magnetic Resonance, 2006, 23(4):451-456.
Li Wei, Xiang Lan, Zhang Jing, Zheng Yinan, Han Likun, Saitoc Masato. A New triterpenoid saponin from the roots of Platycodon grandiflorum. Chin Chem Lett, 2007, 18(3):306-308.
Lei Jun, Li Xiang, Gong Xiao-jie, Zheng Yi-nan. Isolation, synthesis and structures of cytotoxic ginsenoside derivatives. Molecules, 2007, 12(9):2140-2150.
Xu Chun-lian, Zheng Yi-nan, Yang Xiu-wei, Li Xiang-gao, Li Xiang, Chen Quan-cheng. Raddeanalin, a new flavonoid glycoside from the leaves of Salix raddeana Laksh. J Asian Nat Prod Res, 2007, 9(3-5):415-419.
Li Xiang, Lei Jun, Zheng Yi-nan, Sattler Isabel, Lin Wen-han. New ent-Isopimarane Diterpene from Mangrove Excoecaria agallocha L. Chem Res Chinese U, 2007, 23(5):541-543.
Han LK, Morimoto C, Zheng YN, Li Wei, Asami E, Okuda H, Saito M. Effects of Zingerone on Fat Storage in Ovariectomized 家鼠属 YAKUGAKU ZASSHI, 2008, 128(8):1195-1201.
Hu Jiang-ning, Zhu Xue-mei, Han Li-kun, Saito Masato, Sun Yin-shi, Yoshikawa Masayuki, Kimura Yoshiyuki, Zheng Yi-nan. Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata BLUME (Hippocastanaceae). Chem Pharm Bull, 2008, 56(1):12-16.
Li Xiang, Liu Zhi, Zhang Xin-feng, Wang Li-juan, Zheng Yi-nan, Yuan Chang-chun, Sun Guang-zhi. Isolation and characterization of phenolic compounds from the leaves of Salix matsudana. Molecules, 2008, 13(8):1530-1537.
Hu Jiang-ning, Zhu Xun-mei, Lee Ki-Teak, Zheng Yi-nan, Li wei, Han Li-kun, Fang Zhe-ming, Gu Li-juan, Sun Bai-sheng, Wang Chuan-yan, Sung Chang-keun. Optimization of ginsenosides hydrolyzing beta-glucosidase production from Aspergillus niger using response surface methodology. Biol Pharm Bull, 2008, 31(10):1870-1874
Liu Wen-cong, Zheng Yi-nan, Masato Saito, Wang Hai-min, Yoshiyuki Kimura, Ling Ming-song, Feng Yi-xiong. Saponins from stems and leaves of 人参属 quinquefolium prevented high fat diet-induced obesity in mice. Phytomedicine, 2008, 15(12), 1140-11452.
[15]Cao Da-peng, Zheng Yi-nan, Qin Lu-ping, Han T, Zhang H, Rahman K, Zhang Qiao-yan. Curculigo orchioides, a traditional Chinese medicinal 植物界, prevents bone loss in ovariectomized 家鼠属 Maturitas, 2008, 59(4):373-380.
Han Lijun, Li Wei, Han Likun, Hu Jiangning ; Wang zi ; Liu Wencong ; Zheng Yinan. Simultaneous Determination of 22 Pesticides Residues from Stem and Leaves of 人参属 ginseng by 苏黎世草蜢足球俱乐部ECD and GC-MS. Chemia Analityczna, 2009, 54(6):1433-1443.
Yang Zi-juan, Liu Ce-jia, Xiang Lan, Zheng Yi-nan. Phenolic alkaloids as a new class of antioxidants in Portulaca oleracea. Phytother Res., 2009, 23(7):1032-1035
Li Xiang, Liu Zhi, Chen Yun, Wang Li-juan, Zheng Yi-nan, Sun Gang-zhi, Ruan Chang-chun. Rubiacordone A: a new 蒽醌 糖苷 from the roots of Rubia cordifolia. Molecules, 2009, 14(1):566-572
Ruan Chang-chun, Zhang Hao, Zhang Lian-xun, Liu Zhi, Sun Guang-zhi, Lei Jun, Qin Yu-xia, Zheng Yi-nan, Li Xiang, pan Hong-yu. Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase. Molecules, 2009, 14(6):2043-2048.
Li Wei, Zhang Wei, Xiang Lan, Wang Zi, Zheng Yinan, Wang Yingping, Zhang Jing, Chen Li. Platycoside N: A New Oleanane-Type Triterpenoid Saponin from the Roots of Platycodon grandiflorum. Molecules. 2010, 15(12):8702-8708
Li Wei, Liu Zhengbo, Wang Zi, Chen Li, Sun Yinshi, Hou Jingang, Zheng Yinan. Application of accelerated solvent extraction to the investigation of saikosaponins from the roots of Bupleurum falcatum. J Sep Sci. 2010, 33(12):1870-1876.
Li Wei, Wang Zi, Chen Li, Zhang Jing, Han Likun, Hou Jingang, Zheng Yinan. Pressurized liquid extraction followed by LC-ESI/MS for analysis of four chromones in Radix Saposhnikoviae. J. Sep. Sci. 2010, 33(17-18):2881-2887.
Hou Jingang, He Shaoyu, Ling Mingsong, Li Wei, 越南盾 Rui, pan Yongqi, Zheng Yinan. A method of extracting ginsenosides from 人参属 ginseng by pulsed electric field. J. Sep. Sci. 2010, 33(17-18):2707-2713.
Han Mei, Hou Jingang, Dong Chengming, Li Wei, Yu Haolun, Zheng Yinan, Chen Li. Isolation, Synthesis and Structures of Ginsenoside Derivatives and Their Anti-Tumor Bioactivity. Molecules. 2010, 15(1):399-406.
Liu Rui, Zhang Jing-zhao, Liu Wen-cong, Kimura Yoshiyuki, Zheng Yi-nan. Anti-Obesity Effects of Protopanaxdiol Types of Ginsenosides Isolated from the Leaves of American Ginseng (人参属 quinquefolius L.) in Mice Fed with A High-fat Diet. Fitoterapia, 2010, 81(8):1079-1081
Zhang Jing, Shi Lei-ling, Zheng Yi-nan. Dibenzocyclooctadiene lignans from Fructus Schisandrae Chinensis improve glucose uptake in vitro. Nat Prod Commun, 2010, 5(2):231-234
Ruan Chang-chun, Liu Zhi, Li Xiang, Liu Xia, Wang Li-juan, pan Hong-yu, Zheng Yi-nan, Sun Guang-zhi, Zhang Yan-sheng, Zhang Lian-xue. Isolation and Characterization of a New Ginsenoside from the Fresh Root of 人参属 Ginseng. Molecules 2010, 15(4), 2319-2325
Li Wei, Wang Zi, Sun Yinshi, Chen Li, Han Likun, Zheng Yinan. Application of response surface methodology to optimize ultrasonic-assisted extraction of four chromones in Radix Saposhnikoviae, Phytochemical Analysis, 2011, 22(4):313-321.
Li Wei, Zhang Ming, Wang Zi, Zheng Yinan, Wang Yingping, Zhang Jing. Simultaneous RP-HPLC Determination of Six Platycosides: Application to an Enzymatic Preparation Study. Chromatographia. 2011, 74(11-12):777-782
Li Wei, Wang Zi, Wang Ying-ping, Jiang Chao, Liu Qun, Sun Yin-shi, Zheng Yi-nan. Pressurized liquid extraction combining LC-DAD-ESI/MS analysis as an Alternative method to extract three major flavones in Citrus reticulata ‘Chachi’ (Guangchenpi), Food 化学 2012, 130(4):1044-1049.