周慧君 :iDNA网创始人

更新时间:2024-09-21 11:05

周慧君,女,iDNA网创始人,首席执行官,美国医学遗传学会(American Board of Aedical Genetics)资历认证的临床分子遗传学家和美国医学遗传学协会(American College of Medical Genetics)会员,国家食品药品监督管理局特聘技术专家,百华协会北京分会会长。

人物经历

周慧君博士,本科毕业于武汉大学后继赴美留学,在康奈尔大学获得了分子生物和遗传学博士,并在斯坦福大学完成了临床分子基因学的博士后研究。最终获得了美国医学遗传学会(American Board of Medical Genetics)资历认证的临床分子遗传学家和美国医学遗传学协会(American College of Medical Genetics)会员的认证,是国际仅有的323位美国医学遗传学会(ABMG)临床分子遗传学行医执照认证专家,这对于在美留学并成为公认的基因学界的科学家可以说是一难得的成就,在华人科学家领域内也是鲜见的。

通过基因实现个性化医疗是生物遗传学的一个新领域,周慧君博士从事这个领域的工业、科研工作已经超过14年。周慧君博士于1998-2002年领导了Incyte Genomics公司的生物遗传学计划,作为该公司药物遗传学的带头人,她帮助制药公司开展了包括临床药物试验设计在内的药物研发和服务工作。此后周慧君博士在硅谷公司DNA Direct担任资深总监。脱氧核糖核酸 Direct主要提供DNA检测和网上医学遗传学服务,推广以个人基因图谱为指导的医疗服务,以帮助预防疾病,提高生活品质,并实现个性化治疗。

2008年年底,周慧君博士率核心团队回国创业,在北京市正式创建了iDNA网(益基生物科技),成为国内首家互联网基因信息服务平台,同时受邀加入了亚杰商会,并正式成为全球华人生物基因学界的顶级协会-百花协会北京分会会长。在归国之前,iDNA网的核心生物基因技术与商业模式在08年初即获得了全美生物医药商务计划评比第一名,09年在归国后即荣获了创新中国项目展示北京区第二名。并与中国疾病控制中心合作开展了包括北京、武汉市成都市青岛市杭州市哈尔滨市昆明市七个城市的基因与健康的研究项目。2009年参与了科技部国家科技平台重大专项课题研究。

“让每一个中国人更懂自己”是iDNA网的使命,也是创始人周慧君博士的梦想。调查显示:iDNA网的会员近五成是通过口碑相传得知iDNA网并使用基因信息产品;每天来自全国各地不同行业,不同背景,不同健康状况的用户通过iDNA网科学健康地预知了自己未来的生命疾病风险,从而提前进行了医学、饮食、健康作息等干预,高速有效的提升了生命质量,精准、科学、健康的把握住了自己生命的未来。

主要成就

中文论文

[1]保元汤合真武汤联合常规西药治疗慢性心衰的临床观察[J].张秋,尹小星,周慧君.光明中医.2016(16)

中西医结合治疗充血性心衰56例临床观察[J].林楠,尹小星,周慧君.实用中医内科杂志.2011(04)

温阳益气汤治疗慢性充血性心力衰竭临床研究[J].周慧君,尹小星,牛永军.辽宁中医杂志.2010(05)

增率汤治疗病态窦房结综合征临床研究[J].周慧君,尹小星,林楠.辽宁中医杂志.2010(03)

新络合剂治疗不稳定型心绞痛的临床研究[J].周慧君,尹小星,曲燕.光明中医.2010(01)

增率汤治疗病态窦房结综合征的临床观察[J].黄健,周慧君,陈岩辽宁中医杂志.2007(05)

中西医结合治疗充血性心力衰竭的临床观察[J].周慧君,黄健.辽宁中医杂志.2004(10)

英文论文

A Knowledge-Based Decision Framework for Merchandise Systemic Risk 管理学 Under Cross-Broader E-Commerce Pattern[J]. He Junliang,Yan Wei,Huang Youfang,Tan Caimao,Zhou Huijun. Advances in Transdisciplinary Engineering.

Application of the Modality of Multiple Disciplinary Team for a Perioperative Patient with Suspected Novel 正冠状病毒亚科 肺炎 and Cervical Spine Fracture in Nursing[J]. Chen Yuanli,Zhang Yingying,Zhou Huijun,Li Wenzhen,Hao Ruiting,Peng Liang. International Journal of Clinical Medicine. 2020(12)

Infection Prevention Strategy in General Hospital under Regular Epidemic Prevention and Control[J]. Chen Yuanli,Xue Ying,Zhang Yingying,Zhou Huijun,Peng Liang. Open Journal of Preventive Medicine. 2021(04)

Eomes Impedes Durable Response to Tumor Immunotherapy by Inhibiting Stemness, Tissue Residency, and Promoting the Dysfunctional State of Intratumoral CD8+ T Cells

[J]. Sun Runzi,Wu Yixian,Zhou Huijun,Wu Yanshi,Yang Zhongzhou,Gu Yanzheng,Jiang Jingting,Lu Binfeng,Zhu Yibei. Frontiers in Cell and Developmental Biology.

PD-1 Blockade Combined with IL-33 Enhances the Antitumor Immune Response in a Type-1 Lymphocyte-mediated Manner[J]. He Honghong,Shi Liyan,Meng Dan,Zhou Huijun,Ma Jingshu,Wu Yixian,Wu Yanshi,Gu Yanzheng,Xie Wei,Zhang Jing,Zhu Yibei. Cancer Treatment and Research Communications. 2021(prepublish)

Imaging and therapeutic efficacy of "Cu -labeled melanin nanoparticles in A431 tumor -bearing nude mouse models[J]. Zhou Huijun,Li Lin,Cheng Zhen. JOURNAL OF NU.CLEAR MEDICINE.

Cost-effectiveness analysis of glecaprevir/pibrentasvir regimen for treating Chinese patients with chronic hepatitis C genotype 1 and genotype 2 infection.[J]. Zhou HuiJun,Wu Gang,Li JiMing,Naidoo Nasheen,Xie YanXiang,Feng BoLan,Wang Pei,Luo JiWei. Annals of palliative medicine.

Decision and Coordination of Cross-Border E-Commerce Supply Chain: Based on Four Modes of Cooperation[J]. Yan Wei,Zhou Huijun,Li Hui. SCIENTIFIC PROGRAMMING.

Development and validation of a prognostic nomogram for predicting early recurrence after curative resection of stage II/III gastric cancer.[J]. Ma Min,Xiao Haifan,Li Liang,Yin Xianli,Zhou Huijun,Quan Hu,Ouyang Yongzhong,Huang Gang,Li Xiaorong,Xiao Hua. World journal of surgical oncology. 2019(1)

Development and validation of a prognostic nomogram for predicting post-operative pulmonary infection in gastric cancer patients following radical gastrectomy.[J]. Xiao Haifan,Zhou Huijun,Liu Ke,Liao Xianzhen,Yan Shipeng,Yin Bin,Ouyang Yongzhong,Xiao Hua. Scientific reports. 2019(1)

Hierarchically Nanostructured Hybrid Platform for Tumor Delineation and Image-Guided Surgery via NIR-II Fluorescence and PET Bimodal Imaging.[J]. Zhang Qing,Zhou Huijun,Chen Hao,Zhang Xiao,He Shuqing,Ma Lina,Qu Chunrong,Fang Wei,Han Yanjiang,Wang Da,Huang Yuanjian,Sun Yueming,Fan Quli,Chen Yue,Cheng Zhen. Small (Weinheim an der Bergstrasse, Germany). 2019(45)

The effect of preoperative smoking cessation and smoking dose on postoperative complications following radical gastrectomy for gastric cancer: a retrospective study of 2469 patients.[J]. Quan Hu,Ouyang Linda,Zhou Huijun,Ouyang Yongzhong,Xiao Hua. World journal of surgical oncology. 2019(1)

Teaching Evaluation of Modern Chinese History Courses for Different Majors[J]. Huijun Zhou. History Research. 2019(2)

Imaging and therapeutic efficacy of 64labeled melanin nanoparticles in A431 tumor-bearing nude mouse models[J]. Huijun Zhou,Lin Li,Zhen Cheng. The Journal of Nuclear Medicine.

The significant effect of photo-catalyzed redox reactions on the immobilization of by hematite[J]. Liu Jing,Zhu Runliang,Chen Qingze,Zhou Huijun,Liang Xiaoliang,Ma Lingya,Parker Steve C.. Chemical Geology.

TiO 2 /Schwertmannite nanocomposites as superior co-catalysts in heterogeneous photo-Fenton process[J]. Yanping Zhu,Chun Zeng,Runliang Zhu,Yin Xu,Xingyan Wang,Huijun Zhou,Jianxi Zhu,Hongping He. Journal of Environmental Sciences.

Effects of charge density on the hydration of 硅氧烷 surface of 蒙脱石: A molecular 动力学 simulation study[J]. Wei Shen,Lin Li,Huijun Zhou,Qing Zhou,Meng Chen,Jianxi Zhu. Applied Clay Science.

Visible-light Ag/AgBr/ferrihydrite catalyst with enhanced heterogeneous photo-Fenton reactivity via electron transfer from Ag/AgBr to ferrihydrite[J]. Yanping Zhu,Runliang Zhu,Lixia Yan,Haoyang Fu,Yunfei Xi,Huijun Zhou,Gangqiang Zhu,Jianxi Zhu,Hongping 高爆弹 Applied Catalysis B: Environmental.

Hot deformation behaviour and Hansel-Spittel constitutive model of Cr5 alloy for heavy backup roll[J]. Xuewen Chen,Nana Wang,Xiang Ma,Huijun Zhou. Int. J. of Computational Materials Science and surface Engineering. 2018(3/4)

Unusual Uptake of 131I in a Cutaneous Benign Fibrous Histiocytoma in a Patient With Thyroid Cancer[J]. Huijun Zhou,Jiaqi Yan,Rui Huang,Lin Li. Clinical Nuclear Medicine. 2018(1)

NF-κB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling[J]. Fei Bai,Huijun Zhou,Zhongping Fu,Jiangbo Xie,Yingbin Hu,Shaolin Nie. Biomedicine \u0026 Pharmacotherapy.

Molecular Simulation Study on the Interaction of Nanoparticles With Clay Minerals: C60 on Surfaces of 叶蜡石 and Kaolinite[J]. Zhou Huijun,Chen Meng,Zhu Lifang,Li Lin,Zhu Runliang,He Hongping. Clays and Clay Minerals. 2017(6)

In vitro and in vivo evaluation of cationic liposomes containing zoledronic acid as anticancer agent[J]. Xinjun Cai,Zeng Wang,Congyao Wang,Huijun Zhou,Jianjun Ni,Yingying Xu,Liyan Zhu,Tianhong Fu,Fanzhu Li,Sangsang Chen,Jianshe Zhou. Nanomedicine: Nanotechnology, Biology, and Medicine. 2016(2)

Effects of adding bulking agent, inorganic nutrient and microbial inocula on biopile treatment for oil-field drilling waste[J]. Jie Ma,Yongqi Yang,Xiaoli Dai,Yetong Chen,Hanmei Deng,Huijun Zhou,Shaohui Guo,Guangxu Yan. Chemosphere.

Biodistribution and evaluation of 131 I-labeled neuropilin-binding peptide for targeted tumor imaging.[J]. Dong Ping,Cai 华为,Chen Lihong,Li Yalun,Yuan Cen,Wu Xiaoai,Shen Guohua,Zhou Huijun,Zhang Wenjie,Li Lin. Contrast media \u0026 molecular imaging. 2016(6)

^sup 18^F-FDG PET/CT for the Diagnosis of Residual or Recurrent Nasopharyngeal Carcinoma After Radiotherapy: A Metaanalysis[J]. Huijun Zhou,Guohua Shen,Wenjie Zhang,华为 Cai,Yue Zhou,Lin Li. The Journal of Nuclear Medicine. 2016(3)

Diagnostic 表演 of diffusion-weighted magnetic resonance imaging for detection of pelvic metastatic lymph nodes in patients with cervical cancer: A systematic review and meta-analysis.[J]. Shen Guohua,Zhou Huijun,Jia Zhiyun,Deng Houfu. The British journal of radiology.

Machinability of Hastelloy C-276 using Hot-pressed sintered Ti(C7N3)-based cermet cutting tools[J]. Kaitao Xu,Bin Zou,Chuanzhen Huang,Yang Yao,Huijun Zhou,Zhanqiang Liu. Chinese Journal of Mechanical Engineering. 2015(3)

Tool damage and machined-surface quality using hot-pressed sintering Ti(C7N3)/WC/TaC cermet cutting inserts for high-speed turning stainless steels[J]. Bin Zou,Huijun Zhou,Chuanzhen Huang,Kaitao Xu,Jun Wang. The International Journal of Advanced Manufacturing Technology. 2015(1-4)

Formation of birefringence patterns under everyday conditions[J]. Youtian Zhang,Lan Chen,Sihui Wang,Huijun Zhou. European Journal of Physics. 2014(5)

Study of a hot-pressed sintering preparation of Ti(C 7 N 3 )-based composite cermets materials and their 表演 as cutting tools[J]. Bin Zou,Huijun Zhou,Kaitao Xu,Chuanzhen Huang,Jun Wang,Shasha Li. Journal of Alloys and Compounds.

Effects of sintering processes on the mechanical properties and microstructure of Ti(C,N)-based cermet cutting tool materials[J]. Huijun Zhou,Chuanzhen Huang,Bin Zou,Hanlian Liu,Hongtao Zhu,Peng Yao,Jun Wang. International Journal of Refractory Metals and Hard Materials.

GW25-e0396 Progression of carotid atherosclerosis and associated risk factors in elderly Chinese population[J]. Song Canluo,Zhao Chunhua,Nasheen Naidoo,Zhou Huijun,Tong Haiyan. Journal of the American College of Cardiology. 2014(16)

Effects of metal phases and carbides on the microstructure and mechanical properties of Ti(C,N)-based cermets cutting tool materials[J]. Huijun Zhou,Chuanzhen Huang,Bin Zou,Hanlian Liu,Hongtao Zhu,Peng Yao,Jun Wang. Materials Science \u0026 Engineering A.

Angiopoielike protein 2 negatively regulated by microRNA-25 contributes to the malignant progression of colorectal cancer.[J]. Zhou Jumei,Wang Jing,Wu Shengqi,Zhu Suyu,Wang Sai,Zhou Huijun,Tian Xiaoqing,Tang Ning,Nie Shaolin. International journal of molecular medicine. 2014(5)

Unraveling the mystery of the “Maoshan Bugle”[J]. Xu Chen,Ming Qin,Sihui Wang,Huijun Zhou. American Journal of Physics. 2014(2)

Incidence and Clinical Features of Calreticulin mutation in Patients with Jak2V617F-Negative Essential Thrombocytosis and Primary Myelofibrosis from Singapore[J]. Ng Chin Hin,Ng Christopher W.S,Fan Bingwen Eugene,Ong Kiat Hoe,Seah Elaine,Zhou Huijun,Koay Siew Chuan Evelyn,Chng Wee joo Blood. 2014(21)

Coupling between clay swelling/collapse and cationic partition[J]. Huijun Zhou,Meng Chen,Runliang Zhu,Xiancai Lu,Jianxi Zhu,Hongping He. Geochimica et Cosmochimica Acta.

Association between interleukin-36γ and tumor progression in non-small cell lung cancer.[J]. Liu Lin,He Honghong,Xu Dan,Feng Yuehua,Zhou Huijun,Shi Liyan,Gu Yanzheng,Wang Jian,Zhu Yibei. Oncology letters. 2020(3)

Closest-Packing 液态水 Monolayer Stably Intercalated in Phyllosilicate Minerals under High 压强[J]. Chen Meng,Zhou Huijun,Zhu Runliang,Lu Xiancai,He Hongping. Langmuir : the ACS journal of surfaces and colloids. 2020(2)

Expression and clinical significance of CD74 and MMP-9 in colon adenocarcinomas.[J]. Ruan Peng,Gu Yangchun,Zhou Huijun,Zhang Wen,Wang Dingxue,Liang Jinglin,Li Cong. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 2020(2)

[42]压强温度 diagram of wetting and dewetting in a hydrophobic grain boundary and the liquidlike to icelike transition of monolayer 液态水[J]. Meng Chen,Huijun Zhou,Runliang Zhu,Hongping He. Physical Review B. 2020(16)

64 labeled melanin nanoparticles for PET/CT and radionuclide therapy of tumor[J]. Huijun Zhou,Qing Zhang,Yan Cheng,Lili Xiang,Guohua Shen,Xiaoai Wu,华为 Cai,Daifeng Li,Hua Zhu,Ruiping Zhang,Lin Li,Zhen Cheng. Nanomedicine: Nanotechnology, Biology, and Medicine. 2020(prepublish)

Association among the prognostic nutritional index, completion of adjuvant chemotherapy, and cancer-specific survival after curative resection of stage II/III gastric cancer.[J]. Xiao Hua,Zhou Huijun,Zhang Peng,Xiao Haifan,Liu Ke,Chen Xiaoyan,Quan Hu,Yin Bin,Li Rongrong,Huang Gang,Yin Xianli,Ouyang Yongzhong. European journal of clinical nutrition. 2020(4)

Health status and associated factors of HIV-infected patients in Kunming, China.[J]. Li Jing,Wu Chao,Suo Chen,Zhou Huijun,Lu Tian,Lu Lin,Assanangkornchai Sawitri,Chongsuvivatwong Virasakdi,McNeil Edward B,Qiao Chunhong,Wang Jiaping,Wang Pei,Li Yan. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 2020(prepublish)

The Role and Mechanism of S1PR5 in Colon Cancer.[J]. Zhou Huijun,Yin Xianli,Bai Fei,Liu Wu,Jiang Shaofeng,Zhao Jinfeng. Cancer 管理学 and research. 2020(default)

Biodegradable 131 Labeled Microspheres: Potential Transarterial Radioembolization Biomaterial for Primary Hepatocellular Carcinoma Treatment.[J]. Pang Fuwen,Li Yuhao,Zhang Wenjie,Xia Chunchao,He Qing,Li Zhenlin,Xiao Liu,Song Simin,Dong Ping,Zhou Huijun,Shao Tuo,Cai 华为,Li Lin. Advanced healthcare materials. 2020(13)

Health utility of type 2 糖尿病 patients using basal insulin in China: results from the BEYOND II study[J]. Chaoyun Li,HuiJun Zhou,Pei Wang. Acta Diabetologica. 2020(prepublish)

Possible influence of delta-aminolevulinic acid dehydratase polymorphism and susceptibility to renal toxicity of lead: a study of a Vietnamese population.[J]. Chia Sin Eng,Zhou Huijun,Tham Mei Theng,Yap Eric,Dong Nguyen-Viet,Tu Nguyenthi Hong,Chia KEE Seng. Environmental health perspectives. 2005(10)

La possession inaliénable en chinois mandarin et en 法语[J]. Marie-Thérèse Vinet,Huijun Zhou. Cahiers de Linguistique Asie Orientale. 2003(2)

Possibilities of newer ALAD polymorphism influencing human susceptibility to effects of inorganic lead on the neurobehavioral functions[J]. Sin-Eng Chia,Zhou Huijun,Tham Mei Theng,Eric Yap. Neurotoxicology. 2006(2)

Penetrating Keratoplasty in Asian Eyes[J]. Donald T.H. Tan,Prathiba Janardhanan,Huijun Zhou,Yiong-Huak Chan,Hla Myint Htoon,Leonard P.K. Ang,Laurence S. Lim. Ophthalmology. 2007(6)

Possibilities of newer ALAD polymorphism influencing human susceptibility to effects of inorganic lead on the neurobehavioral functions.[J]. Chia Sin-Eng,Huijun Zhou,Theng Tham Mei,Yap Eric. Neurotoxicology. 2007(2)

Penetrating keratoplasty in Asian eyes: the Singapore Corneal Transplant Study.[J]. Tan Donald T H,Janardhanan Prathiba,Zhou Huijun,Chan Yiong-Huak,Htoon Hla Myint,Ang Leonard P K,Lim Laurence S. Ophthalmology. 2008(6)

Experimental study on correlation between sound velocity and solute molecular weight in 聚乙烯 glycol solution[J]. XiangYu Yin,Hao Song,HuiJun Zhou. Science in China Series G: Physics, Mechanics and Astronomy. 2009(1)

获得荣誉

1998年,获得 美国McCormick科学家奖

2001年,获得Incyte发明创新奖

2007年4月12日,《自然》杂志刊登周慧君博士的报道

2008年,获得Morgan Lewis企业家奖

2008年,iDNA网商业模式获得全美生物医药商务计划评比第一名

2009年,iDNA网获得创新中国项目展示北京市第二名

美国医学遗传学会(American Board of Medical Genetics)资历认证的临床分子遗传学家

美国医学遗传学协会(American College of Medical Genetics)资深委员

“人类变异基因工程”(Human Variome)成员

旧金山纪事报》誉为“二十一世纪国际都市青年领袖人物的典范”

参考资料

周慧君_大连市中医医院_万方分析学者知识脉络.万方.2022-01-24

周慧君-作者知网节.知网.2022-01-21

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