更新时间：2024-09-21 14:59
王丹，女，汉族，1982年生，莱斯大学（Rice University）化学工程系和生物工程系访问学者，博士后，硕士生导师，美国化学工程师学会会员、美国微生物学会会员、中国功能材料学会会员，国家自然科学基金函评专家，国家期刊Enzyme and Microbial Technology, Bioresources等杂志审稿人。2017年4月至今，重庆市科学技术局高新技术发展及产业化处副处长（挂职）。
生物催化和代谢工程：主要开展以具有生物活性的酶和全细胞作为催化剂，以可再生生物质为原料的生物催化研究；以生物转化的过程优化为主要研究对象。此外，还开展从头设计的代谢途径研究，计算机模拟技术和湿实验相结合构建细胞工厂。
天然产物和蛋白分离纯化：利用膜分离、吸附及离子交换、亲和色谱等技术，开展天然产物、基因工程药物、酶等的分离工艺及作用机制研究，实现多种生物活性物质的分离纯化如，白藜芦醇，琥珀酸，蛋白A，重组人粒细胞集落刺激因子，重组人上表皮生长因子等的分离纯化。
主持研究国家自然科学基金1项，重庆市自然科学基金2项，南京工业大学材料工程国家重点实验室开放基金1项。作为主要研究人员参与国家973，863及中国科学院星知识创新工程，在本领域重点期刊包括Enzyme and Microbial Technology,Biotechnology and Bioengineering, BioresourceTechnology,BiochemicalJournal,Applied and MicrobiolBiotechnology等发表论文30余篇，其中被SCI收录30篇，发表会议论文8篇，他引245次，申请发明专利5项，美国专利两项，获授权发明专利两项。是国际期刊Enzymeand MicrobialTechnology,Applied and Mic -robiolBiotechnology, Bioresources等杂志审稿人，国家自然科学基金函评专家。2017年6月12日，王丹副教授科研团队发表在Bioresource Technology期刊（SCI 1区，影响因子5.651）上的研究论文The enhancement of the hydrolysis of bamboo biomass in ionic liquid with chitosan-based solid acid catalysts immobilized with metal ions被“可再生能源全球创新”网站（Renewable 能量 Global Innovations）作为Bioenergy进行了特别报道。
主持重庆市自然科学基金：先进燃料生物基脂肪酸及其衍生物的可控合成研究
主持中央高校基本业务费：基于微纳结构壳聚糖微球的合成研究
主持材料化学工程国家重点实验室开放基金：基于微纳结构壳聚糖微球的合成研究
参与中国国家高技术研究发展计划（863计划）（NO.2011AA02A203和2012AA022301）2012-2015
参与中国科学院知识创新工程重要方向项目
主持国家自然科学基金青年基金：利用模块化间隔序列调控人工操纵子构建细胞工厂产琥珀酸的研究
主持重庆市自然科学基金：接枝赖氨酸柔性臂的交联壳聚糖微球固定化酶系统的研究及应用
主持重庆大学优秀青年教师人才引进项目
Le Mi, Dandan, Jie Cheng, Dan Wang*, Sa Li, Xuetuan Wei. 2017. Efficient production of free fatty acids from ionic liquid-based acid- or enzyme-catalyzed bamboo hydrolysate. J. Ind. Microbiol. Biotechnol. 44, 419-430. (*通讯作者，IF=2.81)
Dandan Qin, Yuanliang Hu, Jie Cheng, Nan Wang, Sha Li, Dan Wang*. Au auto-inducibleEscherichia coli strain obtained by adaptively laboratory evolution for fatty acid synthesis from ionic liquid-treated bamboo hydrolystae.Bioresour. Technol., 2016, Sep. 9.(*通讯作者，IF=4.96)
Jie Cheng, Nan Wang, Dezhou Zhao, Dandan Qin, Wenqing Si, Yunfei Tan, Shun’an Wei, Dan Wang*. The enhancement of the hydrolysis of bamboo biomass in ionic liquid with chitosan-based solid acid catalysts immobilized with metal ions.Bioresour. Technol., 2016, Aut. 24. (*通讯作者，IF=4.96)
Wen Jiang, Zhiming Zhou, Dan Wang*, Xiaohua Zhou*, Renyou Tao, Yang Yang, Yexin Shi, Guiluo Zhang, Deyi Wang, Zhen Zhou*. Transglutaminase catalyzed hydrolyzed wheat gliadin grafted with chitosan oligosaccharide and its characterization.Carbohydr. Polym., 2016, Jul. 21. doi:(*通讯作者，IF=3.479)
Dan Wang, Ka-Yiu San*. New pathway to produce hydroxylfatty acid without heterologous expression of hydroxylase.Metab.Eng
Dan Wang, Chandresh Thakker, Ping Liu, George N. Benett, Ka-Yiu San*. Efficient production of free fatty acids from soybeanmeal carbohydrate.Biotechn奥林匹克里昂女子足球队Bioeng., 2015,May 5
Dan Wang, Hui Wu, Chandresh Thakker, Jared Beyersdorf, George N. Benett, Ka-Yiu San*.Efficient free fatty acid production in engineeredEscherichia colistrains using soybean oligosaccharides as feedstock.Biotech.Prog.
Jing Wang, Dandan Qin, Baoyun Zhang, Qiang Li, Lichun Dong, Xiaohua Zhou, Dan Wang*.Fine-tuning of ecaA and pepc gene expression increases succinic acid production inEscherichia coli.APPL Micorbiol. Biotechnol.
Nan Wang, shun’an Wei, Dan Wang*. Chitosan-based solid acid for hydrolysis of bamboo biomass in 1-butyl-3-methylimidazolium 氯化物Green Chem.
Jing Wang, Baoyun Zhang, Jie Zhang, Honghui Wang, Minghui Zhao, Nan Wang, Lichun Dong, Xiaohua Zhou, Dan Wang*. Enhanced succinic acid production and 镁 utilization by overexpression of magnesium transportmgtAinEscherichia coli.Bioresour. Technol.
Nan Wang, Jie Zhang,HonghuiWang,Qiang Li,Sun’anWei, Dan Wang*. Effects of metal ions on the hydrolysis of bamboo biomass in 1-butyl-3-methylimidazolium 氯化物 with dilute acid as catalyst.Bioresour. Technol.
Jie Zhang, Xiaohua Zhou, Dan Wang*, Xing Zhou, Fang Yun, Shiyu Tan. A comprehensive study of extraction of L-lysine with sec-octylphenoxy acetic acid in sulfonated kerosene.Sep. Sci. Technol.
Jie Zhang, Dan Wang*, Jiachuan pan, Jing Wang, Hongbo Zhao, Qiang Li, Xiaohua Zhou. Efficient 白藜芦醇 production by immobilized β-glucosidase on cross-linked chitosan microsphere modified by L-lysine.J. 摩尔 Catal. B-Enzym.
Wang Honghui, Jiachuan pan, Dan Wang*, Jing Wang, Nan Wang, Lin Xu, Qiang Li, Xiaohua Zhou.Succinic acid production from xylose mother liquor by recombinantEscherichia colistrain .Biotechnol.Biotec.eq.
Jing Wang, Qiang Li, Xiaohua Zhou, Dan Wang*. Enhanced succinic acid production and 镁 utilization by overexpression of magnesium transportMgtAinEscherichia coli. 2014, ASM general meeting, 波士顿
Xuetuan Wei,Yinhua Zhou,Jingbang Chen,Dongbo Cai, Dan Wang,Gaofu Qi,Shouwen Chen. Efficient expression of nattokinase inBacillus licheniformis: host strain construction and signal peptide optimization. J Ind Microbiol Biot, 2014
Jing Wang, Honghui Wang, Nan Wang, Qiang Li, Dan Wang*. Combinatorial engineering of intergenic regions in operons to improve the succinic acid production inEscherichia coli. 2014 Fall Meeting, ASM Branches
王丹, 王洪辉, 王竞, 汪楠, 张杰, 邢建民。糠醛和5-羟甲基糠醛对大肠杆菌产丁二酸的影响.中国生物工程学报
Jie Zhang, Xiaohua Zhou*, Dan Wang*, Luyan Sang, Yuanhong peng, Shiyu Tan, Qiang Li. High selective separation of flavonoids based on crosslinked chitosan resin grafted by 槲皮素Sep. Sci. Technol.
Jie Zhang, Xiaohua Zhou *, Dan Wang*, Yingli Wang, Xing Zhou, Honghui Wang, Qiang Li, Shiyu Tan. Studies on the co-immobilized GOD/CAT on cross-linked chitosan microsphere modified by lysine.J. of 摩尔 Catal. B: Enzym.
Jie Zhang, Xiaohua Zhou*, Zhen Zhou, Yu Su, Ruiya Zuo, DanWang*, Shiyu Tan. Preparation and characterization of a novel Ala-Gln dipeptide-Zncomplex.AsianJ.Chem.
Jie Zhang, Xiaohua Zhou, DanWang*, YonghongWang, LinChen,Shiyu Tan.Selective separation of L-aromatic amino acid by L-phenylalanine-crosslinked chitosan resin.AsianJ.Chem.
Qiang Li, Jiandu Lei, Rongyue Zhang, Juan Li, Jianmin Xing, Fei Gao, Fangling Gong, Xaofeng Yan, Dan Wang, Zhiguo Su, Guanghui Ma. Efficient decolorization and deproteinization using uniform polymer microspheres in the succinic acid biorefinery from bio-waste cotton (Gossypium hirsutumL.) stalks.Bioresour. Technol.
Jie Zhang, Xiaohua Zhou, H Xu, Luyan Sang, DanWang*. Selective Adsorption of Flavonoids on Chitosan Resin Grafted by 槲皮素Proc. - Int. Conf. Biomed. Eng. Biotechnol.
Ziyu Song, Qiang Li, Dan Wang, Jie Zhang, and Jianmin Xing. A novel up-flow inner-cycle anoxic bioreactor (UIAB) system for the treatment of 硫化物 wastewater from purification of biogas.液态水 Sci. Technol.
Dan Wang, Qiang Li, Ziyu Song, Wei Zhou, Zhiguo Su, Jianmin Xing. High cell density 发酵 via a metabolically engineeredEscherichia colifor the enhanced production of succinic acid .J.Chem.Technol .Biotechnol.
Qiang Li *, Dan Wang*, Guangyu Hu, Jianmin Xing, Zhiguo Su. Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsoption system.Biochem. Eng. J.
ZelongWang, DanWang, QiangLi, WangliangLi, HuangTang and JianminXing.Enhanced biodesulfurization by expression of dibenzothiophene uptake genes inRhodococcus erythropolis.World J. Microb. Biot.
Dan Wang, Qiang Li, Yu Mao,Jianmin Xing, Zhiguo Su.High-level succinic acid production and yield by α-乳糖induced expression of phosphoenolpyruvate carboxylase inptsGmutantEscherichia coli.APPLMicrobiol. Biotechnol.
Qiang Li, Dan Wang, Ziyu Song, Wei Zhou, Yong Wu, Jianmin Xing, Zhiguo Su.Dual-phase 发酵 enables 放线杆菌属 succinogenes 130ZT to be a potential role for high-level lactate production from the bioresource.Bioresource Technol.
Qiang Li, Dan Wang, Yunjian Li, Yunjian Zhang, Jianmin Xing, Zhiguo Su. One step recovery of succinic acid from 发酵 broths by crystallization.Sep.Purif.Technol.
Qiang Li, Dan Wang, Jianmin Xing, Zhiguo Su.Kinetic evaluation of products inhibition to succinic acid producers Escherichia coli NZN111, AFP111 BL21 and 放线杆菌属 succinogenes 130ZT.J.Microbiol.
Qiang Li, Maohua Yang, Dan Wang, Wangliang Li, Yong Wu, Yunjian Zhang, Jianmin Xing, Zhiguo Su. Efficient conversion of crop stalk wastes into succinic acid production byActinobacillus succinogenes.Bioresour. Technol.
QiangLi, WangliangLi, DanWang, BinbinLiu, HuangTang, MaohuaYang, JianminXing, ZhiguoSu. pH Neutralization while Succinic Acid Adsorption ontoAnion-Exchange Resins.APPL Biochem. Biotechnol.
Dan Wang, Qiang Li,Wangliang Li,Jianmin Xing, Zhiguo Su. Improvement of succinate production by overexpression of a cyanobacterial carbonic anhydrase inEscherichia coli.Enzyme Microbial. Technol.
Wangliang Li, Huang Tang, Qingfen Liu, Jianmin Xing, Qiang Li, DanWang, Maohua Yang, Xin Li, Huizhou Liu. Deep desulfurization of diesel by integrating adsorption and microbial method.Biochem.Eng.J.
Dan Wang, Qiang Li,Wangliang Li,Jianmin Xing, Zhiguo Su. Overexpression of a cyanobacterial carbonic anhydrase inEscherichia colienhances succinic acid production.J. Biotechnol.
D.Wang, Q.Li, Z.Su, J.Xing. Effects of coexpression of carbonic anhydrase and phosphoenolpyruvate carboxylase on succinic acid production inEscherichia coli. The 3rd International Symposium on Advance Biological Engineering and Scienc.
D.Wang, Z.Su, J.Xing. Efficient production of succinic acid from corn stalk hydrolysates by a recombinantEscherichia coliwithptsGmutation. The 2010 International Conference on Biomass 能量 and Technologies.
D.Wang, Q.Li, Z.Song, W.Zhou, J.Xing, Z.Su.High cell density 发酵 of a metabolically engineeredEscherichia coliin fed-batch cultivation for the production of succinic acid. The 2010 International Conference on Biomass 能量 and Technologies.
D.Wang, Q.Li, W.Li, M.Yang, J.Xing, Z.Su. Effects of carbonic anhydrase onsuccinic acid production inEscherichia coli. The 2nd International Symposium on Advance Biological Engineering and Scienc.
D.Wang, Q.Li, W.Li, Q.Liu, J.Xing, Z.Su. Overexpression of a cyanobacterial carbonic anhydrase inEscherichia colienhances succinic acid production. The 13th International Biotechnology Symposium \u0026 Exhibition.
D.Wang, J.Wang, Q.Li, W.Li, J.Xing, Z.Su. Enhanced succinate production by α-乳糖induced expression of phosphoenolpyruvate carboxylase in △ptsGmutantE. coli. The 5th sino-US Joint Conference of Chemical Engineering, 2009, 10.13-10.16, Beijing, China.
王丹, 毛雨, 马兰, 李强, 李望良, 邢建民, 苏志国 α-乳糖诱导丙酮酸羧化酶基因在大肠杆菌中的表达及对琥珀酸产量的影响.生物工程学报
马婕, 王丹, 李强, 邢建民, 刘会洲. 基因工程大肠杆菌合成γ-聚谷氨酸过程工程学报
张玉秀，王姣，王丹，齐峰. 大肠杆菌产琥珀酸基因工程研究进展.中国生物工程杂志
Dexi Wu, Qiang Li, Dan Wang, Yugang 越南盾 Enzymatic hydrolysis and succinic acid 发酵 from steam-exploded corn stalk at high solid concentration by recombinantEscherichia coli.APPL Biochem. Biotechnol.
Dan Wang, Qiang Li, Maohua Yang, Yunjian Zhang, Zhiguo Su, Jianmin Xing. Efficient production of succinic acid from corn stalk hydrolysates by a recombinantEscherichia coliwith ptsG mutation.Process Biochem.
毛雨，王丹, 黄占斌, 邢建民. 微生物原生质体融合育种技术及其应用.中国生物工程杂志
毛雨，王丹，李强，邢建民，黄占斌 产琥珀酸放线杆菌的原生质体制备与再生.中国生物工程杂志
王丹, 王竞, 王洪辉, 汪楠, 周小华 生产丁二酸的重组质粒、基因工程菌的构建及用途. 2013，中国.(第一发明人）
王丹, 王洪辉, 汪楠, 王竞, 周小华. 木糖醇结晶母液制备葡萄糖酸的反应分离耦合装置和工艺. 2013，中国.(第一发明人）
王丹, 汪楠, 魏顺安, 王洪辉, 王竞, 张杰, 周小华. 一种降解木质纤维素生成还原糖的方法. 2013，中国.(第一发明人）
王丹, 周茂祥, 李茹, 蔡锦华, 颜李秀, 周小华 一种制备多孔交联壳聚糖微球的新方法. 2013，中国. (第一发明人）
王丹, 黄小栩, 卢浩, 王孟, 周小华. 一种处理木糖母液的方法. 2011，中国.(第一发明人）
李强, 邢建民, 王丹, 宋子煜, 张云剑. 一种利用离子交换树脂对丁二酸发酵液进行脱色的方法. 2011，中国.(第三发明人）
李强, 邢建民, 王丹, 宋子煜, 张云剑. 一种连续结晶生物制造丁二酸的装置及方法.2011，中国. (第三发明人）
邢建民，周威，李强，李望良，宋子煜，王丹. 一种具有硫酸盐还原功能的柠檬酸杆菌及其应用. 2011，中国.